Artificial hibernation/life-protective state induced by thiazoline-related innate fear odors

Matsuo, Isosaka, et al report that innate fear, but not learned fear, in mice results in systemic hypothermia/hypometabolism and suppressed aerobic metabolism, which enables survival in hypoxic environments. They demonstrate that this process is orchestrated via the brain stem Sp5/NST to midbrain PB...

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Main Authors:	Tomohiko Matsuo, Tomoko Isosaka, Lijun Tang, Tomoyoshi Soga, Reiko Kobayakawa, Ko Kobayakawa
Format:	article
Language:	EN
Published:	Nature Portfolio 2021
Subjects:	Biology (General) QH301-705.5
Online Access:	https://doaj.org/article/bfa63aa7e10d4f18858074c827e1d90a
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spelling	oai:doaj.org-article:bfa63aa7e10d4f18858074c827e1d90a2021-12-02T11:50:30ZArtificial hibernation/life-protective state induced by thiazoline-related innate fear odors10.1038/s42003-020-01629-22399-3642https://doaj.org/article/bfa63aa7e10d4f18858074c827e1d90a2021-01-01T00:00:00Zhttps://doi.org/10.1038/s42003-020-01629-2https://doaj.org/toc/2399-3642Matsuo, Isosaka, et al report that innate fear, but not learned fear, in mice results in systemic hypothermia/hypometabolism and suppressed aerobic metabolism, which enables survival in hypoxic environments. They demonstrate that this process is orchestrated via the brain stem Sp5/NST to midbrain PBN pathway. This study provides insight into the relationship between innate fear and its intrinsic life protective abilitiesTomohiko MatsuoTomoko IsosakaLijun TangTomoyoshi SogaReiko KobayakawaKo KobayakawaNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Tomohiko Matsuo Tomoko Isosaka Lijun Tang Tomoyoshi Soga Reiko Kobayakawa Ko Kobayakawa Artificial hibernation/life-protective state induced by thiazoline-related innate fear odors
description	Matsuo, Isosaka, et al report that innate fear, but not learned fear, in mice results in systemic hypothermia/hypometabolism and suppressed aerobic metabolism, which enables survival in hypoxic environments. They demonstrate that this process is orchestrated via the brain stem Sp5/NST to midbrain PBN pathway. This study provides insight into the relationship between innate fear and its intrinsic life protective abilities
format	article
author	Tomohiko Matsuo Tomoko Isosaka Lijun Tang Tomoyoshi Soga Reiko Kobayakawa Ko Kobayakawa
author_facet	Tomohiko Matsuo Tomoko Isosaka Lijun Tang Tomoyoshi Soga Reiko Kobayakawa Ko Kobayakawa
author_sort	Tomohiko Matsuo
title	Artificial hibernation/life-protective state induced by thiazoline-related innate fear odors
title_short	Artificial hibernation/life-protective state induced by thiazoline-related innate fear odors
title_full	Artificial hibernation/life-protective state induced by thiazoline-related innate fear odors
title_fullStr	Artificial hibernation/life-protective state induced by thiazoline-related innate fear odors
title_full_unstemmed	Artificial hibernation/life-protective state induced by thiazoline-related innate fear odors
title_sort	artificial hibernation/life-protective state induced by thiazoline-related innate fear odors
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/bfa63aa7e10d4f18858074c827e1d90a
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Artificial hibernation/life-protective state induced by thiazoline-related innate fear odors

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