Precision therapeutic targeting of human cancer cell motility
In this study, the authors identify and validate a halogen-substituted isoflavanone able to inhibit prostate cancer cell motility, invasion and metastasis in vitro and in vivo. They demonstrate its ability to selectively inhibit activation of client proteins that stimulate cell motility.
Guardado en:
Autores principales: | Li Xu, Ryan Gordon, Rebecca Farmer, Abhinandan Pattanayak, Andrew Binkowski, Xiaoke Huang, Michael Avram, Sankar Krishna, Eric Voll, Janet Pavese, Juan Chavez, James Bruce, Andrew Mazar, Antoinette Nibbs, Wayne Anderson, Lin Li, Borko Jovanovic, Sean Pruell, Matias Valsecchi, Giulio Francia, Rick Betori, Karl Scheidt, Raymond Bergan |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/bfb4cee65d69447bbe13390df2a07b87 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Soft micromachines with programmable motility and morphology
por: Hen-Wei Huang, et al.
Publicado: (2016) - Neurogastroenterology and motility
- Journal of neurogastroenterology and motility
-
The Effect of Coffee on Spermatozoa Motility and Morphology of BALB/c Mice Exposed to Electric Mosquito Repellent
por: Yehezkiel Andrew Mulyono, et al.
Publicado: (2021) -
Assessing coral sperm motility
por: Nikolas Zuchowicz, et al.
Publicado: (2021)