Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections

Susceptibility to infectious diseases is, among others, influenced by the genetic landscape of the host. Here, Tian and colleagues perform genome-wide association studies for 23 common infections and find 59 risk loci for 17 of these, both within the HLA region and non-HLA loci.

Guardado en:
Detalles Bibliográficos
Autores principales: Chao Tian, Bethann S. Hromatka, Amy K. Kiefer, Nicholas Eriksson, Suzanne M. Noble, Joyce Y. Tung, David A. Hinds
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/bfbc4e10b83b4a8989486628e160061a
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Susceptibility to infectious diseases is, among others, influenced by the genetic landscape of the host. Here, Tian and colleagues perform genome-wide association studies for 23 common infections and find 59 risk loci for 17 of these, both within the HLA region and non-HLA loci.