Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections

Susceptibility to infectious diseases is, among others, influenced by the genetic landscape of the host. Here, Tian and colleagues perform genome-wide association studies for 23 common infections and find 59 risk loci for 17 of these, both within the HLA region and non-HLA loci.

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Autores principales:	Chao Tian, Bethann S. Hromatka, Amy K. Kiefer, Nicholas Eriksson, Suzanne M. Noble, Joyce Y. Tung, David A. Hinds
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bfbc4e10b83b4a8989486628e160061a
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spelling	oai:doaj.org-article:bfbc4e10b83b4a8989486628e160061a2021-12-02T14:42:07ZGenome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections10.1038/s41467-017-00257-52041-1723https://doaj.org/article/bfbc4e10b83b4a8989486628e160061a2017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00257-5https://doaj.org/toc/2041-1723Susceptibility to infectious diseases is, among others, influenced by the genetic landscape of the host. Here, Tian and colleagues perform genome-wide association studies for 23 common infections and find 59 risk loci for 17 of these, both within the HLA region and non-HLA loci.Chao TianBethann S. HromatkaAmy K. KieferNicholas ErikssonSuzanne M. NobleJoyce Y. TungDavid A. HindsNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chao Tian Bethann S. Hromatka Amy K. Kiefer Nicholas Eriksson Suzanne M. Noble Joyce Y. Tung David A. Hinds Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections
description	Susceptibility to infectious diseases is, among others, influenced by the genetic landscape of the host. Here, Tian and colleagues perform genome-wide association studies for 23 common infections and find 59 risk loci for 17 of these, both within the HLA region and non-HLA loci.
format	article
author	Chao Tian Bethann S. Hromatka Amy K. Kiefer Nicholas Eriksson Suzanne M. Noble Joyce Y. Tung David A. Hinds
author_facet	Chao Tian Bethann S. Hromatka Amy K. Kiefer Nicholas Eriksson Suzanne M. Noble Joyce Y. Tung David A. Hinds
author_sort	Chao Tian
title	Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections
title_short	Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections
title_full	Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections
title_fullStr	Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections
title_full_unstemmed	Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections
title_sort	genome-wide association and hla region fine-mapping studies identify susceptibility loci for multiple common infections
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/bfbc4e10b83b4a8989486628e160061a
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Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections

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