mSphere of Influence: Evolutionary Strategies To Sensitize Drug-Resistant Pathogens

ABSTRACT Rebecca S. Shapiro studies antimicrobial resistance and genetic interaction networks. In this mSphere of Influence article, she reflects on how the papers “Bacterial evolution of antibiotic hypersensitivity” by Lázár et al. (V. Lázár, G. Pal Singh, R. Spohn, I. Nagy, et al., Mol Syst Biol 9...

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Auteur principal:	Rebecca S. Shapiro
Format:	article
Langue:	EN
Publié:	American Society for Microbiology 2019
Sujets:	antibiotics antimicrobial drug resistance collateral sensitivity experimental evolution microbial pathogens Microbiology QR1-502
Accès en ligne:	https://doaj.org/article/bfcbeda0df9349769b51aa7dec421149
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id	oai:doaj.org-article:bfcbeda0df9349769b51aa7dec421149
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spelling	oai:doaj.org-article:bfcbeda0df9349769b51aa7dec4211492021-11-15T15:22:21ZmSphere of Influence: Evolutionary Strategies To Sensitize Drug-Resistant Pathogens10.1128/mSphere.00313-192379-5042https://doaj.org/article/bfcbeda0df9349769b51aa7dec4211492019-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSphere.00313-19https://doaj.org/toc/2379-5042ABSTRACT Rebecca S. Shapiro studies antimicrobial resistance and genetic interaction networks. In this mSphere of Influence article, she reflects on how the papers “Bacterial evolution of antibiotic hypersensitivity” by Lázár et al. (V. Lázár, G. Pal Singh, R. Spohn, I. Nagy, et al., Mol Syst Biol 9:700, 2013, https://doi.org/10.1038/msb.2013.57) and “Use of collateral sensitivity networks to design drug cycling protocols that avoid resistance development” by L. Imamovic and M. O. A. Sommer (Sci Transl Med 5:204ra132, 2013, https://doi.org/10.1126/scitranslmed.3006609) impacted her thinking about multigene interaction effects on drug resistance.Rebecca S. ShapiroAmerican Society for Microbiologyarticleantibioticsantimicrobial drug resistancecollateral sensitivityexperimental evolutionmicrobial pathogensMicrobiologyQR1-502ENmSphere, Vol 4, Iss 3 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	antibiotics antimicrobial drug resistance collateral sensitivity experimental evolution microbial pathogens Microbiology QR1-502
spellingShingle	antibiotics antimicrobial drug resistance collateral sensitivity experimental evolution microbial pathogens Microbiology QR1-502 Rebecca S. Shapiro mSphere of Influence: Evolutionary Strategies To Sensitize Drug-Resistant Pathogens
description	ABSTRACT Rebecca S. Shapiro studies antimicrobial resistance and genetic interaction networks. In this mSphere of Influence article, she reflects on how the papers “Bacterial evolution of antibiotic hypersensitivity” by Lázár et al. (V. Lázár, G. Pal Singh, R. Spohn, I. Nagy, et al., Mol Syst Biol 9:700, 2013, https://doi.org/10.1038/msb.2013.57) and “Use of collateral sensitivity networks to design drug cycling protocols that avoid resistance development” by L. Imamovic and M. O. A. Sommer (Sci Transl Med 5:204ra132, 2013, https://doi.org/10.1126/scitranslmed.3006609) impacted her thinking about multigene interaction effects on drug resistance.
format	article
author	Rebecca S. Shapiro
author_facet	Rebecca S. Shapiro
author_sort	Rebecca S. Shapiro
title	mSphere of Influence: Evolutionary Strategies To Sensitize Drug-Resistant Pathogens
title_short	mSphere of Influence: Evolutionary Strategies To Sensitize Drug-Resistant Pathogens
title_full	mSphere of Influence: Evolutionary Strategies To Sensitize Drug-Resistant Pathogens
title_fullStr	mSphere of Influence: Evolutionary Strategies To Sensitize Drug-Resistant Pathogens
title_full_unstemmed	mSphere of Influence: Evolutionary Strategies To Sensitize Drug-Resistant Pathogens
title_sort	msphere of influence: evolutionary strategies to sensitize drug-resistant pathogens
publisher	American Society for Microbiology
publishDate	2019
url	https://doaj.org/article/bfcbeda0df9349769b51aa7dec421149
work_keys_str_mv	AT rebeccasshapiro msphereofinfluenceevolutionarystrategiestosensitizedrugresistantpathogens
_version_	1718428030905352192

mSphere of Influence: Evolutionary Strategies To Sensitize Drug-Resistant Pathogens

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