Optimizing cerebral perfusion and hemodynamics during cardiopulmonary bypass through cannula design combining in silico, in vitro and in vivo input

Abstract Cardiopulmonary bypass (CPB) is a standard technique for cardiac surgery, but comes with the risk of severe neurological complications (e.g. stroke) caused by embolisms and/or reduced cerebral perfusion. We report on an aortic cannula prototype design (optiCAN) with helical outflow and jet-...

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Autores principales: Kristin Hugenroth, Ralf Borchardt, Philine Ritter, Sascha Groß-Hardt, Bart Meyns, Tom Verbelen, Ulrich Steinseifer, Tim A. S. Kaufmann, Ulrich M. Engelmann
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/bfcccda03dbb4c2c899750442f7295d2
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