Genomic Context of Azole Resistance Mutations in <named-content content-type="genus-species">Aspergillus fumigatus</named-content> Determined Using Whole-Genome Sequencing

Genomic Context of Azole Resistance Mutations in <named-content content-type="genus-species">Aspergillus fumigatus</named-content> Determined Using Whole-Genome Sequencing

ABSTRACT A rapid and global emergence of azole resistance has been observed in the pathogenic fungus Aspergillus fumigatus over the past decade. The dominant resistance mechanism appears to be of environmental origin and involves mutations in the cyp51A gene, which encodes a protein targeted by tria...

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Autores principales: Alireza Abdolrasouli, Johanna Rhodes, Mathew A. Beale, Ferry Hagen, Thomas R. Rogers, Anuradha Chowdhary, Jacques F. Meis, Darius Armstrong-James, Matthew C. Fisher
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2015
Materias:
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/bfdb00b29b6c4126b66e655c3581f1ba
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