Rare Orbital Metastasis Originating from Ampullary Adenocarcinoma

Background: Orbital metastasis from ampullary carcinoma is rare, with no previously reported cases. Case presentation: We report the case of a 60-year-old man who complained of a right-sided headache, blurred vision, progressive proptosis, ptosis, and right eye pain for 3 months. His past medical hi...

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Autores principales:	Yung-En Tsai, Ke-Hung Chien, Yao-Feng Li, Shiue-Wei Lai
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	orbital tumor orbital metastasis ampullary carcinoma Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/bfdc3423ea604d4a98eda3d0996ee9de
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spelling	oai:doaj.org-article:bfdc3423ea604d4a98eda3d0996ee9de2021-11-25T18:18:52ZRare Orbital Metastasis Originating from Ampullary Adenocarcinoma10.3390/medicina571112381648-91441010-660Xhttps://doaj.org/article/bfdc3423ea604d4a98eda3d0996ee9de2021-11-01T00:00:00Zhttps://www.mdpi.com/1648-9144/57/11/1238https://doaj.org/toc/1010-660Xhttps://doaj.org/toc/1648-9144Background: Orbital metastasis from ampullary carcinoma is rare, with no previously reported cases. Case presentation: We report the case of a 60-year-old man who complained of a right-sided headache, blurred vision, progressive proptosis, ptosis, and right eye pain for 3 months. His past medical history included an ampullary adenocarcinoma stage IIIA treated via the Whipple procedure and adjuvant chemoradiotherapy 1 year ago. However, he was lost to follow-up. Computed tomography of the orbit showed a soft tissue lesion in the right orbital fossa measuring 3.3 × 2 × 2 cm. An orbital mass biopsy demonstrated an intestinal-type adenocarcinoma that tested positive for cytokeratins 7 and 20 and CDX2 on immunohistochemical staining. The pathologic diagnosis was metastatic adenocarcinoma from the ampulla of Vater. Despite oncological treatment, the patient’s illness progressed. He received palliative treatment and died 1 month later. Conclusions: We presented a rare case of orbital metastasis from ampullary adenocarcinoma. This should be considered in the differential diagnosis of patients with a history of ampullary adenocarcinoma who present with symptoms referring to the relevant locations.Yung-En TsaiKe-Hung ChienYao-Feng LiShiue-Wei LaiMDPI AGarticleorbital tumororbital metastasisampullary carcinomaMedicine (General)R5-920ENMedicina, Vol 57, Iss 1238, p 1238 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	orbital tumor orbital metastasis ampullary carcinoma Medicine (General) R5-920
spellingShingle	orbital tumor orbital metastasis ampullary carcinoma Medicine (General) R5-920 Yung-En Tsai Ke-Hung Chien Yao-Feng Li Shiue-Wei Lai Rare Orbital Metastasis Originating from Ampullary Adenocarcinoma
description	Background: Orbital metastasis from ampullary carcinoma is rare, with no previously reported cases. Case presentation: We report the case of a 60-year-old man who complained of a right-sided headache, blurred vision, progressive proptosis, ptosis, and right eye pain for 3 months. His past medical history included an ampullary adenocarcinoma stage IIIA treated via the Whipple procedure and adjuvant chemoradiotherapy 1 year ago. However, he was lost to follow-up. Computed tomography of the orbit showed a soft tissue lesion in the right orbital fossa measuring 3.3 × 2 × 2 cm. An orbital mass biopsy demonstrated an intestinal-type adenocarcinoma that tested positive for cytokeratins 7 and 20 and CDX2 on immunohistochemical staining. The pathologic diagnosis was metastatic adenocarcinoma from the ampulla of Vater. Despite oncological treatment, the patient’s illness progressed. He received palliative treatment and died 1 month later. Conclusions: We presented a rare case of orbital metastasis from ampullary adenocarcinoma. This should be considered in the differential diagnosis of patients with a history of ampullary adenocarcinoma who present with symptoms referring to the relevant locations.
format	article
author	Yung-En Tsai Ke-Hung Chien Yao-Feng Li Shiue-Wei Lai
author_facet	Yung-En Tsai Ke-Hung Chien Yao-Feng Li Shiue-Wei Lai
author_sort	Yung-En Tsai
title	Rare Orbital Metastasis Originating from Ampullary Adenocarcinoma
title_short	Rare Orbital Metastasis Originating from Ampullary Adenocarcinoma
title_full	Rare Orbital Metastasis Originating from Ampullary Adenocarcinoma
title_fullStr	Rare Orbital Metastasis Originating from Ampullary Adenocarcinoma
title_full_unstemmed	Rare Orbital Metastasis Originating from Ampullary Adenocarcinoma
title_sort	rare orbital metastasis originating from ampullary adenocarcinoma
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/bfdc3423ea604d4a98eda3d0996ee9de
work_keys_str_mv	AT yungentsai rareorbitalmetastasisoriginatingfromampullaryadenocarcinoma AT kehungchien rareorbitalmetastasisoriginatingfromampullaryadenocarcinoma AT yaofengli rareorbitalmetastasisoriginatingfromampullaryadenocarcinoma AT shiueweilai rareorbitalmetastasisoriginatingfromampullaryadenocarcinoma
_version_	1718411344162586624

Rare Orbital Metastasis Originating from Ampullary Adenocarcinoma

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