Epigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus

Epstein-Barr virus (EBV) episomes tether to the host chromosome via EBNA1. Here, using circular chromosome conformation capture (4C), Kim et al. identify attachment sites and show that EBV episomes preferentially associate with transcriptionally silenced genes in Burkitt lymphoma cells.

Guardado en:

Detalles Bibliográficos
Autores principales:	Kyoung-Dong Kim, Hideki Tanizawa, Alessandra De Leo, Olga Vladimirova, Andrew Kossenkov, Fang Lu, Louise C. Showe, Ken-ichi Noma, Paul M. Lieberman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bff55f2ca18e4d65ad7aa6a1d5db6db0
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:bff55f2ca18e4d65ad7aa6a1d5db6db0
record_format	dspace
spelling	oai:doaj.org-article:bff55f2ca18e4d65ad7aa6a1d5db6db02021-12-02T17:33:15ZEpigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus10.1038/s41467-019-14152-82041-1723https://doaj.org/article/bff55f2ca18e4d65ad7aa6a1d5db6db02020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14152-8https://doaj.org/toc/2041-1723Epstein-Barr virus (EBV) episomes tether to the host chromosome via EBNA1. Here, using circular chromosome conformation capture (4C), Kim et al. identify attachment sites and show that EBV episomes preferentially associate with transcriptionally silenced genes in Burkitt lymphoma cells.Kyoung-Dong KimHideki TanizawaAlessandra De LeoOlga VladimirovaAndrew KossenkovFang LuLouise C. ShoweKen-ichi NomaPaul M. LiebermanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kyoung-Dong Kim Hideki Tanizawa Alessandra De Leo Olga Vladimirova Andrew Kossenkov Fang Lu Louise C. Showe Ken-ichi Noma Paul M. Lieberman Epigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus
description	Epstein-Barr virus (EBV) episomes tether to the host chromosome via EBNA1. Here, using circular chromosome conformation capture (4C), Kim et al. identify attachment sites and show that EBV episomes preferentially associate with transcriptionally silenced genes in Burkitt lymphoma cells.
format	article
author	Kyoung-Dong Kim Hideki Tanizawa Alessandra De Leo Olga Vladimirova Andrew Kossenkov Fang Lu Louise C. Showe Ken-ichi Noma Paul M. Lieberman
author_facet	Kyoung-Dong Kim Hideki Tanizawa Alessandra De Leo Olga Vladimirova Andrew Kossenkov Fang Lu Louise C. Showe Ken-ichi Noma Paul M. Lieberman
author_sort	Kyoung-Dong Kim
title	Epigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus
title_short	Epigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus
title_full	Epigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus
title_fullStr	Epigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus
title_full_unstemmed	Epigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus
title_sort	epigenetic specifications of host chromosome docking sites for latent epstein-barr virus
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/bff55f2ca18e4d65ad7aa6a1d5db6db0
work_keys_str_mv	AT kyoungdongkim epigeneticspecificationsofhostchromosomedockingsitesforlatentepsteinbarrvirus AT hidekitanizawa epigeneticspecificationsofhostchromosomedockingsitesforlatentepsteinbarrvirus AT alessandradeleo epigeneticspecificationsofhostchromosomedockingsitesforlatentepsteinbarrvirus AT olgavladimirova epigeneticspecificationsofhostchromosomedockingsitesforlatentepsteinbarrvirus AT andrewkossenkov epigeneticspecificationsofhostchromosomedockingsitesforlatentepsteinbarrvirus AT fanglu epigeneticspecificationsofhostchromosomedockingsitesforlatentepsteinbarrvirus AT louisecshowe epigeneticspecificationsofhostchromosomedockingsitesforlatentepsteinbarrvirus AT kenichinoma epigeneticspecificationsofhostchromosomedockingsitesforlatentepsteinbarrvirus AT paulmlieberman epigeneticspecificationsofhostchromosomedockingsitesforlatentepsteinbarrvirus
_version_	1718380024232411136

Epigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus

Ejemplares similares