Subtraction-free and bisulfite-free specific sequencing of 5-methylcytosine and its oxidized derivatives at base resolution

Specific and quantitative sequencing of cytosine modifications is challenging at base-resolution. Here the authors present TAPSβ and CAPS for subtraction-free whole genome sequencing of 5mC and 5hmC.

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Autores principales:	Yibin Liu, Zhiyuan Hu, Jingfei Cheng, Paulina Siejka-Zielińska, Jinfeng Chen, Masato Inoue, Ahmed Ashour Ahmed, Chun-Xiao Song
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bff59ff2b80449c5bd60715c079a9f1f
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spelling	oai:doaj.org-article:bff59ff2b80449c5bd60715c079a9f1f2021-12-02T13:57:32ZSubtraction-free and bisulfite-free specific sequencing of 5-methylcytosine and its oxidized derivatives at base resolution10.1038/s41467-021-20920-22041-1723https://doaj.org/article/bff59ff2b80449c5bd60715c079a9f1f2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-20920-2https://doaj.org/toc/2041-1723Specific and quantitative sequencing of cytosine modifications is challenging at base-resolution. Here the authors present TAPSβ and CAPS for subtraction-free whole genome sequencing of 5mC and 5hmC.Yibin LiuZhiyuan HuJingfei ChengPaulina Siejka-ZielińskaJinfeng ChenMasato InoueAhmed Ashour AhmedChun-Xiao SongNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yibin Liu Zhiyuan Hu Jingfei Cheng Paulina Siejka-Zielińska Jinfeng Chen Masato Inoue Ahmed Ashour Ahmed Chun-Xiao Song Subtraction-free and bisulfite-free specific sequencing of 5-methylcytosine and its oxidized derivatives at base resolution
description	Specific and quantitative sequencing of cytosine modifications is challenging at base-resolution. Here the authors present TAPSβ and CAPS for subtraction-free whole genome sequencing of 5mC and 5hmC.
format	article
author	Yibin Liu Zhiyuan Hu Jingfei Cheng Paulina Siejka-Zielińska Jinfeng Chen Masato Inoue Ahmed Ashour Ahmed Chun-Xiao Song
author_facet	Yibin Liu Zhiyuan Hu Jingfei Cheng Paulina Siejka-Zielińska Jinfeng Chen Masato Inoue Ahmed Ashour Ahmed Chun-Xiao Song
author_sort	Yibin Liu
title	Subtraction-free and bisulfite-free specific sequencing of 5-methylcytosine and its oxidized derivatives at base resolution
title_short	Subtraction-free and bisulfite-free specific sequencing of 5-methylcytosine and its oxidized derivatives at base resolution
title_full	Subtraction-free and bisulfite-free specific sequencing of 5-methylcytosine and its oxidized derivatives at base resolution
title_fullStr	Subtraction-free and bisulfite-free specific sequencing of 5-methylcytosine and its oxidized derivatives at base resolution
title_full_unstemmed	Subtraction-free and bisulfite-free specific sequencing of 5-methylcytosine and its oxidized derivatives at base resolution
title_sort	subtraction-free and bisulfite-free specific sequencing of 5-methylcytosine and its oxidized derivatives at base resolution
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/bff59ff2b80449c5bd60715c079a9f1f
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Subtraction-free and bisulfite-free specific sequencing of 5-methylcytosine and its oxidized derivatives at base resolution

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