2021 Asian Pacific Society of Cardiology Consensus Recommendations on the Use of P2Y12 Receptor Antagonists in the Asia-Pacific Region: Special Populations
Advanced age, diabetes, and chronic kidney disease not only increase the risk for ischaemic events in chronic coronary syndromes (CCS) but also confer a high bleeding risk during antiplatelet therapy. These special populations may warrant modification of therapy, especially among Asians, who have di...
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Radcliffe Medical Media
2021
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oai:doaj.org-article:bffbfa97e42d4e47b8f838fe9e3ad4502021-12-04T16:05:18Z2021 Asian Pacific Society of Cardiology Consensus Recommendations on the Use of P2Y12 Receptor Antagonists in the Asia-Pacific Region: Special Populations10.15420/ecr.2021.351758-37641758-3756https://doaj.org/article/bffbfa97e42d4e47b8f838fe9e3ad4502021-11-01T00:00:00Zhttps://www.ecrjournal.com/articleindex/ecr.2021.35https://doaj.org/toc/1758-3756https://doaj.org/toc/1758-3764Advanced age, diabetes, and chronic kidney disease not only increase the risk for ischaemic events in chronic coronary syndromes (CCS) but also confer a high bleeding risk during antiplatelet therapy. These special populations may warrant modification of therapy, especially among Asians, who have displayed characteristics that are clinically distinct from Western patients. Previous guidance has been provided regarding the classification of high-risk CCS and the use of newer-generation P2Y12 inhibitors (i.e. ticagrelor and prasugrel) after acute coronary syndromes (ACS) in Asia. The authors summarise evidence on the use of these P2Y12 inhibitors during the transition from ACS to CCS and among special populations. Specifically, they present recommendations on the roles of standard dual antiplatelet therapy, shortened dual antiplatelet therapy and single antiplatelet therapy among patients with coronary artery disease, who are either transitioning from ACS to CCS; elderly; or with chronic kidney disease, diabetes, multivessel coronary artery disease and bleeding events during therapy.Jack Wei Chieh TanDerek P ChewKin Lam TsuiDoreen TanDmitry DuplyakovAyman HammoudehBo ZhangYi LiKai XuPaul J OngDoni FirmanHabib GamraWael AlmahmeedJamshed DalalLi-Wah TamGabriel StegQuang N NguyenJunya AkoJassim Al SuwaidiMark ChanMohamed SobhyAbdulla ShehabWacin BuddhariZulu WangAlan Yean Yip FongBilgehan KaradagByeong-Keuk KimUsman BaberChee Tang ChinYa Ling HanRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENEuropean Cardiology Review , Vol 16, Iss , Pp - (2021) |
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Diseases of the circulatory (Cardiovascular) system RC666-701 |
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Diseases of the circulatory (Cardiovascular) system RC666-701 Jack Wei Chieh Tan Derek P Chew Kin Lam Tsui Doreen Tan Dmitry Duplyakov Ayman Hammoudeh Bo Zhang Yi Li Kai Xu Paul J Ong Doni Firman Habib Gamra Wael Almahmeed Jamshed Dalal Li-Wah Tam Gabriel Steg Quang N Nguyen Junya Ako Jassim Al Suwaidi Mark Chan Mohamed Sobhy Abdulla Shehab Wacin Buddhari Zulu Wang Alan Yean Yip Fong Bilgehan Karadag Byeong-Keuk Kim Usman Baber Chee Tang Chin Ya Ling Han 2021 Asian Pacific Society of Cardiology Consensus Recommendations on the Use of P2Y12 Receptor Antagonists in the Asia-Pacific Region: Special Populations |
description |
Advanced age, diabetes, and chronic kidney disease not only increase the risk for ischaemic events in chronic coronary syndromes (CCS) but also confer a high bleeding risk during antiplatelet therapy. These special populations may warrant modification of therapy, especially among Asians, who have displayed characteristics that are clinically distinct from Western patients. Previous guidance has been provided regarding the classification of high-risk CCS and the use of newer-generation P2Y12 inhibitors (i.e. ticagrelor and prasugrel) after acute coronary syndromes (ACS) in Asia. The authors summarise evidence on the use of these P2Y12 inhibitors during the transition from ACS to CCS and among special populations. Specifically, they present recommendations on the roles of standard dual antiplatelet therapy, shortened dual antiplatelet therapy and single antiplatelet therapy among patients with coronary artery disease, who are either transitioning from ACS to CCS; elderly; or with chronic kidney disease, diabetes, multivessel coronary artery disease and bleeding events during therapy. |
format |
article |
author |
Jack Wei Chieh Tan Derek P Chew Kin Lam Tsui Doreen Tan Dmitry Duplyakov Ayman Hammoudeh Bo Zhang Yi Li Kai Xu Paul J Ong Doni Firman Habib Gamra Wael Almahmeed Jamshed Dalal Li-Wah Tam Gabriel Steg Quang N Nguyen Junya Ako Jassim Al Suwaidi Mark Chan Mohamed Sobhy Abdulla Shehab Wacin Buddhari Zulu Wang Alan Yean Yip Fong Bilgehan Karadag Byeong-Keuk Kim Usman Baber Chee Tang Chin Ya Ling Han |
author_facet |
Jack Wei Chieh Tan Derek P Chew Kin Lam Tsui Doreen Tan Dmitry Duplyakov Ayman Hammoudeh Bo Zhang Yi Li Kai Xu Paul J Ong Doni Firman Habib Gamra Wael Almahmeed Jamshed Dalal Li-Wah Tam Gabriel Steg Quang N Nguyen Junya Ako Jassim Al Suwaidi Mark Chan Mohamed Sobhy Abdulla Shehab Wacin Buddhari Zulu Wang Alan Yean Yip Fong Bilgehan Karadag Byeong-Keuk Kim Usman Baber Chee Tang Chin Ya Ling Han |
author_sort |
Jack Wei Chieh Tan |
title |
2021 Asian Pacific Society of Cardiology Consensus Recommendations on the Use of P2Y12 Receptor Antagonists in the Asia-Pacific Region: Special Populations |
title_short |
2021 Asian Pacific Society of Cardiology Consensus Recommendations on the Use of P2Y12 Receptor Antagonists in the Asia-Pacific Region: Special Populations |
title_full |
2021 Asian Pacific Society of Cardiology Consensus Recommendations on the Use of P2Y12 Receptor Antagonists in the Asia-Pacific Region: Special Populations |
title_fullStr |
2021 Asian Pacific Society of Cardiology Consensus Recommendations on the Use of P2Y12 Receptor Antagonists in the Asia-Pacific Region: Special Populations |
title_full_unstemmed |
2021 Asian Pacific Society of Cardiology Consensus Recommendations on the Use of P2Y12 Receptor Antagonists in the Asia-Pacific Region: Special Populations |
title_sort |
2021 asian pacific society of cardiology consensus recommendations on the use of p2y12 receptor antagonists in the asia-pacific region: special populations |
publisher |
Radcliffe Medical Media |
publishDate |
2021 |
url |
https://doaj.org/article/bffbfa97e42d4e47b8f838fe9e3ad450 |
work_keys_str_mv |
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