2021 Asian Pacific Society of Cardiology Consensus Recommendations on the Use of P2Y12 Receptor Antagonists in the Asia-Pacific Region: Special Populations

Advanced age, diabetes, and chronic kidney disease not only increase the risk for ischaemic events in chronic coronary syndromes (CCS) but also confer a high bleeding risk during antiplatelet therapy. These special populations may warrant modification of therapy, especially among Asians, who have di...

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Autores principales: Jack Wei Chieh Tan, Derek P Chew, Kin Lam Tsui, Doreen Tan, Dmitry Duplyakov, Ayman Hammoudeh, Bo Zhang, Yi Li, Kai Xu, Paul J Ong, Doni Firman, Habib Gamra, Wael Almahmeed, Jamshed Dalal, Li-Wah Tam, Gabriel Steg, Quang N Nguyen, Junya Ako, Jassim Al Suwaidi, Mark Chan, Mohamed Sobhy, Abdulla Shehab, Wacin Buddhari, Zulu Wang, Alan Yean Yip Fong, Bilgehan Karadag, Byeong-Keuk Kim, Usman Baber, Chee Tang Chin, Ya Ling Han
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Publicado: Radcliffe Medical Media 2021
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Acceso en línea:https://doaj.org/article/bffbfa97e42d4e47b8f838fe9e3ad450
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spelling oai:doaj.org-article:bffbfa97e42d4e47b8f838fe9e3ad4502021-12-04T16:05:18Z2021 Asian Pacific Society of Cardiology Consensus Recommendations on the Use of P2Y12 Receptor Antagonists in the Asia-Pacific Region: Special Populations10.15420/ecr.2021.351758-37641758-3756https://doaj.org/article/bffbfa97e42d4e47b8f838fe9e3ad4502021-11-01T00:00:00Zhttps://www.ecrjournal.com/articleindex/ecr.2021.35https://doaj.org/toc/1758-3756https://doaj.org/toc/1758-3764Advanced age, diabetes, and chronic kidney disease not only increase the risk for ischaemic events in chronic coronary syndromes (CCS) but also confer a high bleeding risk during antiplatelet therapy. These special populations may warrant modification of therapy, especially among Asians, who have displayed characteristics that are clinically distinct from Western patients. Previous guidance has been provided regarding the classification of high-risk CCS and the use of newer-generation P2Y12 inhibitors (i.e. ticagrelor and prasugrel) after acute coronary syndromes (ACS) in Asia. The authors summarise evidence on the use of these P2Y12 inhibitors during the transition from ACS to CCS and among special populations. Specifically, they present recommendations on the roles of standard dual antiplatelet therapy, shortened dual antiplatelet therapy and single antiplatelet therapy among patients with coronary artery disease, who are either transitioning from ACS to CCS; elderly; or with chronic kidney disease, diabetes, multivessel coronary artery disease and bleeding events during therapy.Jack Wei Chieh TanDerek P ChewKin Lam TsuiDoreen TanDmitry DuplyakovAyman HammoudehBo ZhangYi LiKai XuPaul J OngDoni FirmanHabib GamraWael AlmahmeedJamshed DalalLi-Wah TamGabriel StegQuang N NguyenJunya AkoJassim Al SuwaidiMark ChanMohamed SobhyAbdulla ShehabWacin BuddhariZulu WangAlan Yean Yip FongBilgehan KaradagByeong-Keuk KimUsman BaberChee Tang ChinYa Ling HanRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENEuropean Cardiology Review , Vol 16, Iss , Pp - (2021)
institution DOAJ
collection DOAJ
language EN
topic Diseases of the circulatory (Cardiovascular) system
RC666-701
spellingShingle Diseases of the circulatory (Cardiovascular) system
RC666-701
Jack Wei Chieh Tan
Derek P Chew
Kin Lam Tsui
Doreen Tan
Dmitry Duplyakov
Ayman Hammoudeh
Bo Zhang
Yi Li
Kai Xu
Paul J Ong
Doni Firman
Habib Gamra
Wael Almahmeed
Jamshed Dalal
Li-Wah Tam
Gabriel Steg
Quang N Nguyen
Junya Ako
Jassim Al Suwaidi
Mark Chan
Mohamed Sobhy
Abdulla Shehab
Wacin Buddhari
Zulu Wang
Alan Yean Yip Fong
Bilgehan Karadag
Byeong-Keuk Kim
Usman Baber
Chee Tang Chin
Ya Ling Han
2021 Asian Pacific Society of Cardiology Consensus Recommendations on the Use of P2Y12 Receptor Antagonists in the Asia-Pacific Region: Special Populations
description Advanced age, diabetes, and chronic kidney disease not only increase the risk for ischaemic events in chronic coronary syndromes (CCS) but also confer a high bleeding risk during antiplatelet therapy. These special populations may warrant modification of therapy, especially among Asians, who have displayed characteristics that are clinically distinct from Western patients. Previous guidance has been provided regarding the classification of high-risk CCS and the use of newer-generation P2Y12 inhibitors (i.e. ticagrelor and prasugrel) after acute coronary syndromes (ACS) in Asia. The authors summarise evidence on the use of these P2Y12 inhibitors during the transition from ACS to CCS and among special populations. Specifically, they present recommendations on the roles of standard dual antiplatelet therapy, shortened dual antiplatelet therapy and single antiplatelet therapy among patients with coronary artery disease, who are either transitioning from ACS to CCS; elderly; or with chronic kidney disease, diabetes, multivessel coronary artery disease and bleeding events during therapy.
format article
author Jack Wei Chieh Tan
Derek P Chew
Kin Lam Tsui
Doreen Tan
Dmitry Duplyakov
Ayman Hammoudeh
Bo Zhang
Yi Li
Kai Xu
Paul J Ong
Doni Firman
Habib Gamra
Wael Almahmeed
Jamshed Dalal
Li-Wah Tam
Gabriel Steg
Quang N Nguyen
Junya Ako
Jassim Al Suwaidi
Mark Chan
Mohamed Sobhy
Abdulla Shehab
Wacin Buddhari
Zulu Wang
Alan Yean Yip Fong
Bilgehan Karadag
Byeong-Keuk Kim
Usman Baber
Chee Tang Chin
Ya Ling Han
author_facet Jack Wei Chieh Tan
Derek P Chew
Kin Lam Tsui
Doreen Tan
Dmitry Duplyakov
Ayman Hammoudeh
Bo Zhang
Yi Li
Kai Xu
Paul J Ong
Doni Firman
Habib Gamra
Wael Almahmeed
Jamshed Dalal
Li-Wah Tam
Gabriel Steg
Quang N Nguyen
Junya Ako
Jassim Al Suwaidi
Mark Chan
Mohamed Sobhy
Abdulla Shehab
Wacin Buddhari
Zulu Wang
Alan Yean Yip Fong
Bilgehan Karadag
Byeong-Keuk Kim
Usman Baber
Chee Tang Chin
Ya Ling Han
author_sort Jack Wei Chieh Tan
title 2021 Asian Pacific Society of Cardiology Consensus Recommendations on the Use of P2Y12 Receptor Antagonists in the Asia-Pacific Region: Special Populations
title_short 2021 Asian Pacific Society of Cardiology Consensus Recommendations on the Use of P2Y12 Receptor Antagonists in the Asia-Pacific Region: Special Populations
title_full 2021 Asian Pacific Society of Cardiology Consensus Recommendations on the Use of P2Y12 Receptor Antagonists in the Asia-Pacific Region: Special Populations
title_fullStr 2021 Asian Pacific Society of Cardiology Consensus Recommendations on the Use of P2Y12 Receptor Antagonists in the Asia-Pacific Region: Special Populations
title_full_unstemmed 2021 Asian Pacific Society of Cardiology Consensus Recommendations on the Use of P2Y12 Receptor Antagonists in the Asia-Pacific Region: Special Populations
title_sort 2021 asian pacific society of cardiology consensus recommendations on the use of p2y12 receptor antagonists in the asia-pacific region: special populations
publisher Radcliffe Medical Media
publishDate 2021
url https://doaj.org/article/bffbfa97e42d4e47b8f838fe9e3ad450
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