Nod2 and Nod2-regulated microbiota protect BALB/c mice from diet-induced obesity and metabolic dysfunction
Abstract Genetics plays a central role in susceptibility to obesity and metabolic diseases. BALB/c mice are known to be resistant to high fat diet (HFD)-induced obesity, however the genetic cause remains unknown. We report that deletion of the innate immunity antibacterial gene Nod2 abolishes this r...
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Main Authors: | Ivan Rodriguez-Nunez, Tiffany Caluag, Kori Kirby, Charles N. Rudick, Roman Dziarski, Dipika Gupta |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
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Online Access: | https://doaj.org/article/c00e8f898783402ab063d1e8e5fbaf3f |
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