The role of lipids in the pathophysiology of coronavirus infections

Coronaviruses, which have been known to cause diseases in animals since the 1930s, utilize cellular components during their replication cycle. Lipids play important roles in viral infection, as coronaviruses target cellular lipids and lipid metabolism to modify their host cells to become an optimal...

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Autores principales: Milad Zandi, Parastoo Hosseini, Saber Soltani, Azadeh Rasooli, Mona Moghadami, Sepideh Nasimzadeh, Farzane Behnezhad
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Lenguaje:EN
Publicado: Korea Centers for Disease Control & Prevention 2021
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Acceso en línea:https://doaj.org/article/c011424fd1e4498aa5122c85017a17c6
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spelling oai:doaj.org-article:c011424fd1e4498aa5122c85017a17c62021-11-05T00:07:51ZThe role of lipids in the pathophysiology of coronavirus infections2210-90992210-911010.24171/j.phrp.2021.0153https://doaj.org/article/c011424fd1e4498aa5122c85017a17c62021-10-01T00:00:00Zhttp://ophrp.org/upload/pdf/j-phrp-2021-0153.pdfhttps://doaj.org/toc/2210-9099https://doaj.org/toc/2210-9110Coronaviruses, which have been known to cause diseases in animals since the 1930s, utilize cellular components during their replication cycle. Lipids play important roles in viral infection, as coronaviruses target cellular lipids and lipid metabolism to modify their host cells to become an optimal environment for viral replication. Therefore, lipids can be considered as potential targets for the development of antiviral agents. This review provides an overview of the roles of cellular lipids in different stages of the life cycle of coronaviruses.Milad ZandiParastoo HosseiniSaber SoltaniAzadeh RasooliMona MoghadamiSepideh NasimzadehFarzane BehnezhadKorea Centers for Disease Control & Preventionarticlehuman coronaviruseslipidsmetabolismsars-cov-2Special situations and conditionsRC952-1245Infectious and parasitic diseasesRC109-216ENOsong Public Health and Research Perspectives, Vol 12, Iss 5, Pp 278-285 (2021)
institution DOAJ
collection DOAJ
language EN
topic human coronaviruses
lipids
metabolism
sars-cov-2
Special situations and conditions
RC952-1245
Infectious and parasitic diseases
RC109-216
spellingShingle human coronaviruses
lipids
metabolism
sars-cov-2
Special situations and conditions
RC952-1245
Infectious and parasitic diseases
RC109-216
Milad Zandi
Parastoo Hosseini
Saber Soltani
Azadeh Rasooli
Mona Moghadami
Sepideh Nasimzadeh
Farzane Behnezhad
The role of lipids in the pathophysiology of coronavirus infections
description Coronaviruses, which have been known to cause diseases in animals since the 1930s, utilize cellular components during their replication cycle. Lipids play important roles in viral infection, as coronaviruses target cellular lipids and lipid metabolism to modify their host cells to become an optimal environment for viral replication. Therefore, lipids can be considered as potential targets for the development of antiviral agents. This review provides an overview of the roles of cellular lipids in different stages of the life cycle of coronaviruses.
format article
author Milad Zandi
Parastoo Hosseini
Saber Soltani
Azadeh Rasooli
Mona Moghadami
Sepideh Nasimzadeh
Farzane Behnezhad
author_facet Milad Zandi
Parastoo Hosseini
Saber Soltani
Azadeh Rasooli
Mona Moghadami
Sepideh Nasimzadeh
Farzane Behnezhad
author_sort Milad Zandi
title The role of lipids in the pathophysiology of coronavirus infections
title_short The role of lipids in the pathophysiology of coronavirus infections
title_full The role of lipids in the pathophysiology of coronavirus infections
title_fullStr The role of lipids in the pathophysiology of coronavirus infections
title_full_unstemmed The role of lipids in the pathophysiology of coronavirus infections
title_sort role of lipids in the pathophysiology of coronavirus infections
publisher Korea Centers for Disease Control & Prevention
publishDate 2021
url https://doaj.org/article/c011424fd1e4498aa5122c85017a17c6
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