Signaling through Syk or CARD9 Mediates Species-Specific Anti-<italic toggle="yes">Candida</italic> Protection in Bone Marrow Chimeric Mice

Signaling through Syk or CARD9 Mediates Species-Specific Anti-<italic toggle="yes">Candida</italic> Protection in Bone Marrow Chimeric Mice

ABSTRACT The spleen tyrosine kinase (Syk) and the downstream adaptor protein CARD9 are crucial signaling molecules in antimicrobial immunity. Candida parapsilosis is an emerging fungal pathogen with a high incidence in neonates, while Candida albicans is the most common agent of candidiasis. While s...

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Autores principales: Erik Zajta, Katalin Csonka, Adél Tóth, Laszló Tiszlavicz, Tamás Németh, Anita Orosz, Ádám Novák, Máté Csikós, Csaba Vágvölgyi, Attila Mócsai, Attila Gácser
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
Materias:
Candida parapsilosis
Candida albicans
Syk
CARD9
antifungal immunity
antifungal immune therapy
Microbiology
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Acceso en línea:https://doaj.org/article/c011d03ff5bf4b71b4e56284953a58df
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