Activin signaling is an essential component of the TGF-β induced pro-metastatic phenotype in colorectal cancer

Activin signaling is an essential component of the TGF-β induced pro-metastatic phenotype in colorectal cancer

Abstract Advanced colorectal cancer (CRC) remains a critical health care challenge worldwide. Various TGF-β superfamily members are important in colorectal cancer metastasis, but their signaling effects and predictive value have only been assessed in isolation. Here, we examine cross-regulation and...

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Autores principales: Jonas J. Staudacher, Jessica Bauer, Arundhati Jana, Jun Tian, Timothy Carroll, Georgina Mancinelli, Özkan Özden, Nancy Krett, Grace Guzman, David Kerr, Paul Grippo, Barbara Jung
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/c01c74d63eaa498fb7379bdbd225836e
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