Antibiotic susceptibility signatures identify potential antimicrobial targets in the Acinetobacter baumannii cell envelope

A unique cell envelope contributes to the antibiotic resistance of the pathogen Acinetobacter baumannii. Here, Geisinger et al. identify A. baumannii mutants with altered antibiotic susceptibility, infer the function of uncharacterized proteins involved in envelope synthesis, and predict antibiotic...

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Autores principales:	Edward Geisinger, Nadav J. Mortman, Yunfei Dai, Murat Cokol, Sapna Syal, Andrew Farinha, Delaney G. Fisher, Amy Y. Tang, David W. Lazinski, Stephen Wood, Jon Anthony, Tim van Opijnen, Ralph R. Isberg
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c02ae759b9cd41e7bac28dc223d59326
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spelling	oai:doaj.org-article:c02ae759b9cd41e7bac28dc223d593262021-12-02T18:03:07ZAntibiotic susceptibility signatures identify potential antimicrobial targets in the Acinetobacter baumannii cell envelope10.1038/s41467-020-18301-22041-1723https://doaj.org/article/c02ae759b9cd41e7bac28dc223d593262020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18301-2https://doaj.org/toc/2041-1723A unique cell envelope contributes to the antibiotic resistance of the pathogen Acinetobacter baumannii. Here, Geisinger et al. identify A. baumannii mutants with altered antibiotic susceptibility, infer the function of uncharacterized proteins involved in envelope synthesis, and predict antibiotic synergies.Edward GeisingerNadav J. MortmanYunfei DaiMurat CokolSapna SyalAndrew FarinhaDelaney G. FisherAmy Y. TangDavid W. LazinskiStephen WoodJon AnthonyTim van OpijnenRalph R. IsbergNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Edward Geisinger Nadav J. Mortman Yunfei Dai Murat Cokol Sapna Syal Andrew Farinha Delaney G. Fisher Amy Y. Tang David W. Lazinski Stephen Wood Jon Anthony Tim van Opijnen Ralph R. Isberg Antibiotic susceptibility signatures identify potential antimicrobial targets in the Acinetobacter baumannii cell envelope
description	A unique cell envelope contributes to the antibiotic resistance of the pathogen Acinetobacter baumannii. Here, Geisinger et al. identify A. baumannii mutants with altered antibiotic susceptibility, infer the function of uncharacterized proteins involved in envelope synthesis, and predict antibiotic synergies.
format	article
author	Edward Geisinger Nadav J. Mortman Yunfei Dai Murat Cokol Sapna Syal Andrew Farinha Delaney G. Fisher Amy Y. Tang David W. Lazinski Stephen Wood Jon Anthony Tim van Opijnen Ralph R. Isberg
author_facet	Edward Geisinger Nadav J. Mortman Yunfei Dai Murat Cokol Sapna Syal Andrew Farinha Delaney G. Fisher Amy Y. Tang David W. Lazinski Stephen Wood Jon Anthony Tim van Opijnen Ralph R. Isberg
author_sort	Edward Geisinger
title	Antibiotic susceptibility signatures identify potential antimicrobial targets in the Acinetobacter baumannii cell envelope
title_short	Antibiotic susceptibility signatures identify potential antimicrobial targets in the Acinetobacter baumannii cell envelope
title_full	Antibiotic susceptibility signatures identify potential antimicrobial targets in the Acinetobacter baumannii cell envelope
title_fullStr	Antibiotic susceptibility signatures identify potential antimicrobial targets in the Acinetobacter baumannii cell envelope
title_full_unstemmed	Antibiotic susceptibility signatures identify potential antimicrobial targets in the Acinetobacter baumannii cell envelope
title_sort	antibiotic susceptibility signatures identify potential antimicrobial targets in the acinetobacter baumannii cell envelope
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/c02ae759b9cd41e7bac28dc223d59326
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Antibiotic susceptibility signatures identify potential antimicrobial targets in the Acinetobacter baumannii cell envelope

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