Positive Anti-GABAB Receptor Antibodies in a Patient with Hashimoto’s Thyroiditis and Bipolar Affective Disorder

A kind of autoimmune encephalitis with positive autoantibodies toward the B1 subunit of the gamma-aminobutyric acid-type B receptor is known as anti-GABABR encephalitis. It is an autoimmune brain disorder with typical manifestations of a limbic encephalitis. It can coexist with positive anti-thyroid...

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Autores principales:	Polina A. Sobolevskaia, Boris V. Andreev, Leonid P. Churilov, Tamara V. Fedotkina, Boris Gilburd, Aliya K. Stanova, Vladimir J. Utekhin, Yehuda Shoenfeld
Formato:	article
Lenguaje:	EN
Publicado:	Karger Publishers 2021
Materias:	hashimoto’s thyroiditis psychiatric disorders bipolar affective disorder autoimmunity Medicine R
Acceso en línea:	https://doaj.org/article/c02e202f1c9343f3887beb13dcc8e7eb
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spelling	oai:doaj.org-article:c02e202f1c9343f3887beb13dcc8e7eb2021-11-25T07:47:21ZPositive Anti-GABAB Receptor Antibodies in a Patient with Hashimoto’s Thyroiditis and Bipolar Affective Disorder2571-726X10.1159/000518554https://doaj.org/article/c02e202f1c9343f3887beb13dcc8e7eb2021-10-01T00:00:00Zhttps://www.karger.com/Article/FullText/518554https://doaj.org/toc/2571-726XA kind of autoimmune encephalitis with positive autoantibodies toward the B1 subunit of the gamma-aminobutyric acid-type B receptor is known as anti-GABABR encephalitis. It is an autoimmune brain disorder with typical manifestations of a limbic encephalitis. It can coexist with positive anti-thyroid autoantibodies. We described a 57-year-old woman who was diagnosed with a bipolar affective disorder. The patient had high titers of anti-thyroid peroxidase antibodies, and she also was positive for anti-GABABR antibodies. There is a question, if this case is a kind of comorbidity of anti-thyroid and anti-brain autoimmunity or is it a single nosological entity – a kind of Hashimoto’s encephalopathy?Polina A. SobolevskaiaBoris V. AndreevLeonid P. ChurilovTamara V. FedotkinaBoris GilburdAliya K. StanovaVladimir J. UtekhinYehuda ShoenfeldKarger Publishersarticlehashimoto’s thyroiditispsychiatric disordersbipolar affective disorderautoimmunityMedicineRENDubai Medical Journal, Pp 1-3 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	hashimoto’s thyroiditis psychiatric disorders bipolar affective disorder autoimmunity Medicine R
spellingShingle	hashimoto’s thyroiditis psychiatric disorders bipolar affective disorder autoimmunity Medicine R Polina A. Sobolevskaia Boris V. Andreev Leonid P. Churilov Tamara V. Fedotkina Boris Gilburd Aliya K. Stanova Vladimir J. Utekhin Yehuda Shoenfeld Positive Anti-GABAB Receptor Antibodies in a Patient with Hashimoto’s Thyroiditis and Bipolar Affective Disorder
description	A kind of autoimmune encephalitis with positive autoantibodies toward the B1 subunit of the gamma-aminobutyric acid-type B receptor is known as anti-GABABR encephalitis. It is an autoimmune brain disorder with typical manifestations of a limbic encephalitis. It can coexist with positive anti-thyroid autoantibodies. We described a 57-year-old woman who was diagnosed with a bipolar affective disorder. The patient had high titers of anti-thyroid peroxidase antibodies, and she also was positive for anti-GABABR antibodies. There is a question, if this case is a kind of comorbidity of anti-thyroid and anti-brain autoimmunity or is it a single nosological entity – a kind of Hashimoto’s encephalopathy?
format	article
author	Polina A. Sobolevskaia Boris V. Andreev Leonid P. Churilov Tamara V. Fedotkina Boris Gilburd Aliya K. Stanova Vladimir J. Utekhin Yehuda Shoenfeld
author_facet	Polina A. Sobolevskaia Boris V. Andreev Leonid P. Churilov Tamara V. Fedotkina Boris Gilburd Aliya K. Stanova Vladimir J. Utekhin Yehuda Shoenfeld
author_sort	Polina A. Sobolevskaia
title	Positive Anti-GABAB Receptor Antibodies in a Patient with Hashimoto’s Thyroiditis and Bipolar Affective Disorder
title_short	Positive Anti-GABAB Receptor Antibodies in a Patient with Hashimoto’s Thyroiditis and Bipolar Affective Disorder
title_full	Positive Anti-GABAB Receptor Antibodies in a Patient with Hashimoto’s Thyroiditis and Bipolar Affective Disorder
title_fullStr	Positive Anti-GABAB Receptor Antibodies in a Patient with Hashimoto’s Thyroiditis and Bipolar Affective Disorder
title_full_unstemmed	Positive Anti-GABAB Receptor Antibodies in a Patient with Hashimoto’s Thyroiditis and Bipolar Affective Disorder
title_sort	positive anti-gabab receptor antibodies in a patient with hashimoto’s thyroiditis and bipolar affective disorder
publisher	Karger Publishers
publishDate	2021
url	https://doaj.org/article/c02e202f1c9343f3887beb13dcc8e7eb
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Positive Anti-GABAB Receptor Antibodies in a Patient with Hashimoto’s Thyroiditis and Bipolar Affective Disorder

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