ROLE OF PAX-5 TRANSCRIPTION FACTOR IN IMMUNOLOGICAL PROCESSES
Abstract. The review article concerns various features of PAX-5 (paired box 5) transcription factor, its structure, functions, regulation of activity, involvement into differentiation and activation of B lymphocytes, switching to IgE synthesis, its role in oncogenesis, and a putative r...
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| Main Authors: | , , , , |
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| Format: | article |
| Language: | RU |
| Published: |
SPb RAACI
2014
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| Subjects: | |
| Online Access: | https://doaj.org/article/c03e99b7abf6428cb2dbdeda96bcdfe4 |
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| Summary: | Abstract. The review article concerns various features of PAX-5 (paired box 5) transcription factor, its structure, functions, regulation of activity, involvement into differentiation and activation of B lymphocytes, switching to IgE synthesis, its role in oncogenesis, and a putative role of this factor for development of bronchial asthma.Further insight into specific properties of PAX-5 factor in bronchial asthma may provide a promising approach to studying mechanisms of this disorder. (Med. Immunol., 2011, vol. 13, N 6, pp 569-580) |
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