ROLE OF PAX-5 TRANSCRIPTION FACTOR IN IMMUNOLOGICAL PROCESSES

Abstract.  The  review  article  concerns  various  features  of  PAX-5  (paired  box  5)  transcription  factor,  its structure, functions, regulation of activity, involvement into differentiation and activation of B lymphocytes, switching to IgE synthesis, its role in oncogenesis, and a putative r...

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Autores principales: V. N. Mineev, L. N. Sorokina, M. A. Nyoma, V. A. Ivanov, G. I. Lipkin
Formato: article
Lenguaje:RU
Publicado: SPb RAACI 2014
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ige
Acceso en línea:https://doaj.org/article/c03e99b7abf6428cb2dbdeda96bcdfe4
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spelling oai:doaj.org-article:c03e99b7abf6428cb2dbdeda96bcdfe42021-11-18T08:03:42ZROLE OF PAX-5 TRANSCRIPTION FACTOR IN IMMUNOLOGICAL PROCESSES1563-06252313-741X10.15789/1563-0625-2011-6-569-580https://doaj.org/article/c03e99b7abf6428cb2dbdeda96bcdfe42014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/597https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract.  The  review  article  concerns  various  features  of  PAX-5  (paired  box  5)  transcription  factor,  its structure, functions, regulation of activity, involvement into differentiation and activation of B lymphocytes, switching to IgE synthesis, its role in oncogenesis, and a putative role of this factor for development of bronchial asthma.Further  insight  into  specific  properties  of  PAX-5  factor  in  bronchial  asthma  may  provide  a  promising approach to studying mechanisms of this disorder. (Med. Immunol., 2011, vol. 13, N 6, pp 569-580)V. N. MineevL. N. SorokinaM. A. NyomaV. A. IvanovG. I. LipkinSPb RAACIarticlepax-5transcription factorsb lymphocytesbronchial asthmaigeImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 13, Iss 6, Pp 569-580 (2014)
institution DOAJ
collection DOAJ
language RU
topic pax-5
transcription factors
b lymphocytes
bronchial asthma
ige
Immunologic diseases. Allergy
RC581-607
spellingShingle pax-5
transcription factors
b lymphocytes
bronchial asthma
ige
Immunologic diseases. Allergy
RC581-607
V. N. Mineev
L. N. Sorokina
M. A. Nyoma
V. A. Ivanov
G. I. Lipkin
ROLE OF PAX-5 TRANSCRIPTION FACTOR IN IMMUNOLOGICAL PROCESSES
description Abstract.  The  review  article  concerns  various  features  of  PAX-5  (paired  box  5)  transcription  factor,  its structure, functions, regulation of activity, involvement into differentiation and activation of B lymphocytes, switching to IgE synthesis, its role in oncogenesis, and a putative role of this factor for development of bronchial asthma.Further  insight  into  specific  properties  of  PAX-5  factor  in  bronchial  asthma  may  provide  a  promising approach to studying mechanisms of this disorder. (Med. Immunol., 2011, vol. 13, N 6, pp 569-580)
format article
author V. N. Mineev
L. N. Sorokina
M. A. Nyoma
V. A. Ivanov
G. I. Lipkin
author_facet V. N. Mineev
L. N. Sorokina
M. A. Nyoma
V. A. Ivanov
G. I. Lipkin
author_sort V. N. Mineev
title ROLE OF PAX-5 TRANSCRIPTION FACTOR IN IMMUNOLOGICAL PROCESSES
title_short ROLE OF PAX-5 TRANSCRIPTION FACTOR IN IMMUNOLOGICAL PROCESSES
title_full ROLE OF PAX-5 TRANSCRIPTION FACTOR IN IMMUNOLOGICAL PROCESSES
title_fullStr ROLE OF PAX-5 TRANSCRIPTION FACTOR IN IMMUNOLOGICAL PROCESSES
title_full_unstemmed ROLE OF PAX-5 TRANSCRIPTION FACTOR IN IMMUNOLOGICAL PROCESSES
title_sort role of pax-5 transcription factor in immunological processes
publisher SPb RAACI
publishDate 2014
url https://doaj.org/article/c03e99b7abf6428cb2dbdeda96bcdfe4
work_keys_str_mv AT vnmineev roleofpax5transcriptionfactorinimmunologicalprocesses
AT lnsorokina roleofpax5transcriptionfactorinimmunologicalprocesses
AT manyoma roleofpax5transcriptionfactorinimmunologicalprocesses
AT vaivanov roleofpax5transcriptionfactorinimmunologicalprocesses
AT gilipkin roleofpax5transcriptionfactorinimmunologicalprocesses
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