The Mycobacterium tuberculosis FAS-II dehydratases and methyltransferases define the specificity of the mycolic acid elongation complexes.

<h4>Background</h4>The human pathogen Mycobacterium tuberculosis (Mtb) has the originality of possessing a multifunctional mega-enzyme FAS-I (Fatty Acid Synthase-I), together with a multi-protein FAS-II system, to carry out the biosynthesis of common and of specific long chain fatty acid...

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Auteurs principaux: Sylvain Cantaloube, Romain Veyron-Churlet, Nabila Haddache, Mamadou Daffé, Didier Zerbib
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
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R
Q
Accès en ligne:https://doaj.org/article/c068d5605e7d4b988c72f8814c5ec2cc
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