Gold nanoparticles enhance antibody effect through direct cancer cell cytotoxicity by differential regulation of phagocytosis

Gold nanoparticles enhance antibody effect through direct cancer cell cytotoxicity by differential regulation of phagocytosis

Antibody therapies have huge potential in treating cancer but currently suffer from problems with delivery. Here the authors report on a study into then conjugation of Ramucirumab to gold nanoparticles to improve delivery and add theranostic capabilities, demonstrating preferential toxicity in gastr...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Linyang Fan, Weizhi Wang, Zihua Wang, Minzhi Zhao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/c0796a15b6a146ae8c4ca7d66a98469c
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:c0796a15b6a146ae8c4ca7d66a98469c
record_format dspace
spelling oai:doaj.org-article:c0796a15b6a146ae8c4ca7d66a98469c2021-11-08T11:05:57ZGold nanoparticles enhance antibody effect through direct cancer cell cytotoxicity by differential regulation of phagocytosis10.1038/s41467-021-26694-x2041-1723https://doaj.org/article/c0796a15b6a146ae8c4ca7d66a98469c2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26694-xhttps://doaj.org/toc/2041-1723Antibody therapies have huge potential in treating cancer but currently suffer from problems with delivery. Here the authors report on a study into then conjugation of Ramucirumab to gold nanoparticles to improve delivery and add theranostic capabilities, demonstrating preferential toxicity in gastric cancer cells.Linyang FanWeizhi WangZihua WangMinzhi ZhaoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Linyang Fan
Weizhi Wang
Zihua Wang
Minzhi Zhao
Gold nanoparticles enhance antibody effect through direct cancer cell cytotoxicity by differential regulation of phagocytosis
description Antibody therapies have huge potential in treating cancer but currently suffer from problems with delivery. Here the authors report on a study into then conjugation of Ramucirumab to gold nanoparticles to improve delivery and add theranostic capabilities, demonstrating preferential toxicity in gastric cancer cells.
format article
author Linyang Fan
Weizhi Wang
Zihua Wang
Minzhi Zhao
author_facet Linyang Fan
Weizhi Wang
Zihua Wang
Minzhi Zhao
author_sort Linyang Fan
title Gold nanoparticles enhance antibody effect through direct cancer cell cytotoxicity by differential regulation of phagocytosis
title_short Gold nanoparticles enhance antibody effect through direct cancer cell cytotoxicity by differential regulation of phagocytosis
title_full Gold nanoparticles enhance antibody effect through direct cancer cell cytotoxicity by differential regulation of phagocytosis
title_fullStr Gold nanoparticles enhance antibody effect through direct cancer cell cytotoxicity by differential regulation of phagocytosis
title_full_unstemmed Gold nanoparticles enhance antibody effect through direct cancer cell cytotoxicity by differential regulation of phagocytosis
title_sort gold nanoparticles enhance antibody effect through direct cancer cell cytotoxicity by differential regulation of phagocytosis
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/c0796a15b6a146ae8c4ca7d66a98469c
work_keys_str_mv AT linyangfan goldnanoparticlesenhanceantibodyeffectthroughdirectcancercellcytotoxicitybydifferentialregulationofphagocytosis
AT weizhiwang goldnanoparticlesenhanceantibodyeffectthroughdirectcancercellcytotoxicitybydifferentialregulationofphagocytosis
AT zihuawang goldnanoparticlesenhanceantibodyeffectthroughdirectcancercellcytotoxicitybydifferentialregulationofphagocytosis
AT minzhizhao goldnanoparticlesenhanceantibodyeffectthroughdirectcancercellcytotoxicitybydifferentialregulationofphagocytosis
_version_ 1718442371022061568

Ejemplares similares