NuA4 and SAGA acetyltransferase complexes cooperate for repair of DNA breaks by homologous recombination.

Chromatin modifying complexes play important yet not fully defined roles in DNA repair processes. The essential NuA4 histone acetyltransferase (HAT) complex is recruited to double-strand break (DSB) sites and spreads along with DNA end resection. As predicted, NuA4 acetylates surrounding nucleosomes...

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Autores principales: Xue Cheng, Valérie Côté, Jacques Côté
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/c07c9a3c9fda49bf89c41828cf83325a
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