Induction of autophagy by a novel small molecule improves aβ pathology and ameliorates cognitive deficits.

Growing evidence has demonstrated a neuroprotective role of autophagy in Alzheimer's disease (AD). Thus, autophagy has been regarded as a potential therapeutic target, attracting increasing interest in pharmaceutical autophagy modulation by small molecules. We designed a two-cycle screening str...

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Détails bibliographiques
Auteurs principaux: Cheng Chu, Xinjiang Zhang, Wei Ma, Li Li, Wei Wang, Lu Shang, Peng Fu
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
Sujets:
R
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Accès en ligne:https://doaj.org/article/c07d0e99046f4a42acff63418245e074
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