Induction of autophagy by a novel small molecule improves aβ pathology and ameliorates cognitive deficits.
Growing evidence has demonstrated a neuroprotective role of autophagy in Alzheimer's disease (AD). Thus, autophagy has been regarded as a potential therapeutic target, attracting increasing interest in pharmaceutical autophagy modulation by small molecules. We designed a two-cycle screening str...
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Auteurs principaux: | Cheng Chu, Xinjiang Zhang, Wei Ma, Li Li, Wei Wang, Lu Shang, Peng Fu |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2013
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Accès en ligne: | https://doaj.org/article/c07d0e99046f4a42acff63418245e074 |
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