From signal-based to comprehensive magnetic resonance imaging

Abstract We present and evaluate a new insight into magnetic resonance imaging (MRI). It is based on the algebraic description of the magnetization during the transient response—including intrinsic magnetic resonance parameters such as longitudinal and transverse relaxation times (T1, T2) and proton...

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Autores principales:	Gyula Kotek, Laura Nunez-Gonzalez, Mika W. Vogel, Gabriel P. Krestin, Dirk H. J. Poot, Juan A. Hernandez-Tamames
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/c086dc06a7cc40b4bf150b5477bf160d
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spelling	oai:doaj.org-article:c086dc06a7cc40b4bf150b5477bf160d2021-12-02T16:35:05ZFrom signal-based to comprehensive magnetic resonance imaging10.1038/s41598-021-96791-w2045-2322https://doaj.org/article/c086dc06a7cc40b4bf150b5477bf160d2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-96791-whttps://doaj.org/toc/2045-2322Abstract We present and evaluate a new insight into magnetic resonance imaging (MRI). It is based on the algebraic description of the magnetization during the transient response—including intrinsic magnetic resonance parameters such as longitudinal and transverse relaxation times (T1, T2) and proton density (PD) and experimental conditions such as radiofrequency field (B1) and constant/homogeneous magnetic field (B0) from associated scanners. We exploit the correspondence among three different elements: the signal evolution as a result of a repetitive sequence of blocks of radiofrequency excitation pulses and encoding gradients, the continuous Bloch equations and the mathematical description of a sequence as a linear system. This approach simultaneously provides, in a single measurement, all quantitative parameters of interest as well as associated system imperfections. Finally, we demonstrate the in-vivo applicability of the new concept on a clinical MRI scanner.Gyula KotekLaura Nunez-GonzalezMika W. VogelGabriel P. KrestinDirk H. J. PootJuan A. Hernandez-TamamesNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Gyula Kotek Laura Nunez-Gonzalez Mika W. Vogel Gabriel P. Krestin Dirk H. J. Poot Juan A. Hernandez-Tamames From signal-based to comprehensive magnetic resonance imaging
description	Abstract We present and evaluate a new insight into magnetic resonance imaging (MRI). It is based on the algebraic description of the magnetization during the transient response—including intrinsic magnetic resonance parameters such as longitudinal and transverse relaxation times (T1, T2) and proton density (PD) and experimental conditions such as radiofrequency field (B1) and constant/homogeneous magnetic field (B0) from associated scanners. We exploit the correspondence among three different elements: the signal evolution as a result of a repetitive sequence of blocks of radiofrequency excitation pulses and encoding gradients, the continuous Bloch equations and the mathematical description of a sequence as a linear system. This approach simultaneously provides, in a single measurement, all quantitative parameters of interest as well as associated system imperfections. Finally, we demonstrate the in-vivo applicability of the new concept on a clinical MRI scanner.
format	article
author	Gyula Kotek Laura Nunez-Gonzalez Mika W. Vogel Gabriel P. Krestin Dirk H. J. Poot Juan A. Hernandez-Tamames
author_facet	Gyula Kotek Laura Nunez-Gonzalez Mika W. Vogel Gabriel P. Krestin Dirk H. J. Poot Juan A. Hernandez-Tamames
author_sort	Gyula Kotek
title	From signal-based to comprehensive magnetic resonance imaging
title_short	From signal-based to comprehensive magnetic resonance imaging
title_full	From signal-based to comprehensive magnetic resonance imaging
title_fullStr	From signal-based to comprehensive magnetic resonance imaging
title_full_unstemmed	From signal-based to comprehensive magnetic resonance imaging
title_sort	from signal-based to comprehensive magnetic resonance imaging
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/c086dc06a7cc40b4bf150b5477bf160d
work_keys_str_mv	AT gyulakotek fromsignalbasedtocomprehensivemagneticresonanceimaging AT lauranunezgonzalez fromsignalbasedtocomprehensivemagneticresonanceimaging AT mikawvogel fromsignalbasedtocomprehensivemagneticresonanceimaging AT gabrielpkrestin fromsignalbasedtocomprehensivemagneticresonanceimaging AT dirkhjpoot fromsignalbasedtocomprehensivemagneticresonanceimaging AT juanahernandeztamames fromsignalbasedtocomprehensivemagneticresonanceimaging
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From signal-based to comprehensive magnetic resonance imaging

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