Solubility; still a challenging subject in pharmaceutical sciences
Solubility of a drug/drug candidate is one of the most important required physico-chemical properties in pharmaceutical area and nearly 40% of drug candidates fail to proceed to the higher trial phases of new drug development process because of their poor solubility. The commonly used method is to d...
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Universidad de Antioquia
2010
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oai:doaj.org-article:c08b8df18d4a4accb80c0d7e9af53c3f2021-11-19T04:14:19ZSolubility; still a challenging subject in pharmaceutical sciences0121-40042145-2660https://doaj.org/article/c08b8df18d4a4accb80c0d7e9af53c3f2010-11-01T00:00:00Zhttps://revistas.udea.edu.co/index.php/vitae/article/view/7426https://doaj.org/toc/0121-4004https://doaj.org/toc/2145-2660Solubility of a drug/drug candidate is one of the most important required physico-chemical properties in pharmaceutical area and nearly 40% of drug candidates fail to proceed to the higher trial phases of new drug development process because of their poor solubility. The commonly used method is to determine the experimental values of either thermodynamic or kinetic solubility. Numerous efforts were made to develop predictive tools for replacing the time consuming and costly experimental methods.Abolghasem JouybanUniversidad de AntioquiaarticleFood processing and manufactureTP368-456Pharmaceutical industryHD9665-9675ENVitae, Vol 17, Iss 3 (2010) |
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Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675 |
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Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675 Abolghasem Jouyban Solubility; still a challenging subject in pharmaceutical sciences |
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Solubility of a drug/drug candidate is one of the most important required physico-chemical properties in pharmaceutical area and nearly 40% of drug candidates fail to proceed to the higher trial phases of new drug development process because of their poor solubility. The commonly used method is to determine the experimental values of either thermodynamic or kinetic solubility. Numerous efforts were made to develop predictive tools for replacing the time consuming and costly experimental methods. |
format |
article |
author |
Abolghasem Jouyban |
author_facet |
Abolghasem Jouyban |
author_sort |
Abolghasem Jouyban |
title |
Solubility; still a challenging subject in pharmaceutical sciences |
title_short |
Solubility; still a challenging subject in pharmaceutical sciences |
title_full |
Solubility; still a challenging subject in pharmaceutical sciences |
title_fullStr |
Solubility; still a challenging subject in pharmaceutical sciences |
title_full_unstemmed |
Solubility; still a challenging subject in pharmaceutical sciences |
title_sort |
solubility; still a challenging subject in pharmaceutical sciences |
publisher |
Universidad de Antioquia |
publishDate |
2010 |
url |
https://doaj.org/article/c08b8df18d4a4accb80c0d7e9af53c3f |
work_keys_str_mv |
AT abolghasemjouyban solubilitystillachallengingsubjectinpharmaceuticalsciences |
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1718420517913886720 |