Solubility; still a challenging subject in pharmaceutical sciences

Solubility of a drug/drug candidate is one of the most important required physico-chemical properties in pharmaceutical area and nearly 40% of drug candidates fail to proceed to the higher trial phases of new drug development process because of their poor solubility. The commonly used method is to d...

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Auteur principal: Abolghasem Jouyban
Format: article
Langue:EN
Publié: Universidad de Antioquia 2010
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spelling oai:doaj.org-article:c08b8df18d4a4accb80c0d7e9af53c3f2021-11-19T04:14:19ZSolubility; still a challenging subject in pharmaceutical sciences0121-40042145-2660https://doaj.org/article/c08b8df18d4a4accb80c0d7e9af53c3f2010-11-01T00:00:00Zhttps://revistas.udea.edu.co/index.php/vitae/article/view/7426https://doaj.org/toc/0121-4004https://doaj.org/toc/2145-2660Solubility of a drug/drug candidate is one of the most important required physico-chemical properties in pharmaceutical area and nearly 40% of drug candidates fail to proceed to the higher trial phases of new drug development process because of their poor solubility. The commonly used method is to determine the experimental values of either thermodynamic or kinetic solubility. Numerous efforts were made to develop predictive tools for replacing the time consuming and costly experimental methods.Abolghasem JouybanUniversidad de AntioquiaarticleFood processing and manufactureTP368-456Pharmaceutical industryHD9665-9675ENVitae, Vol 17, Iss 3 (2010)
institution DOAJ
collection DOAJ
language EN
topic Food processing and manufacture
TP368-456
Pharmaceutical industry
HD9665-9675
spellingShingle Food processing and manufacture
TP368-456
Pharmaceutical industry
HD9665-9675
Abolghasem Jouyban
Solubility; still a challenging subject in pharmaceutical sciences
description Solubility of a drug/drug candidate is one of the most important required physico-chemical properties in pharmaceutical area and nearly 40% of drug candidates fail to proceed to the higher trial phases of new drug development process because of their poor solubility. The commonly used method is to determine the experimental values of either thermodynamic or kinetic solubility. Numerous efforts were made to develop predictive tools for replacing the time consuming and costly experimental methods.
format article
author Abolghasem Jouyban
author_facet Abolghasem Jouyban
author_sort Abolghasem Jouyban
title Solubility; still a challenging subject in pharmaceutical sciences
title_short Solubility; still a challenging subject in pharmaceutical sciences
title_full Solubility; still a challenging subject in pharmaceutical sciences
title_fullStr Solubility; still a challenging subject in pharmaceutical sciences
title_full_unstemmed Solubility; still a challenging subject in pharmaceutical sciences
title_sort solubility; still a challenging subject in pharmaceutical sciences
publisher Universidad de Antioquia
publishDate 2010
url https://doaj.org/article/c08b8df18d4a4accb80c0d7e9af53c3f
work_keys_str_mv AT abolghasemjouyban solubilitystillachallengingsubjectinpharmaceuticalsciences
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