The olfactory epithelium as a port of entry in neonatal neurolisteriosis

Listeria monocytogenes causes meningitis in newborns. Here, Pägelow et al. present a mouse model of neonatal cerebral listeriosis, and show that nasal inoculation, but not intragastric administration, leads to early brain infection in the absence of bacteraemia during the neonatal period.

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Detalles Bibliográficos
Autores principales: Dennis Pägelow, Chintan Chhatbar, Andreas Beineke, Xiaokun Liu, Andreas Nerlich, Kira van Vorst, Manfred Rohde, Ulrich Kalinke, Reinhold Förster, Stephan Halle, Peter Valentin-Weigand, Mathias W. Hornef, Marcus Fulde
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/c08c113f11854074a92f5cc129f573b3
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Sumario:Listeria monocytogenes causes meningitis in newborns. Here, Pägelow et al. present a mouse model of neonatal cerebral listeriosis, and show that nasal inoculation, but not intragastric administration, leads to early brain infection in the absence of bacteraemia during the neonatal period.