The olfactory epithelium as a port of entry in neonatal neurolisteriosis

Listeria monocytogenes causes meningitis in newborns. Here, Pägelow et al. present a mouse model of neonatal cerebral listeriosis, and show that nasal inoculation, but not intragastric administration, leads to early brain infection in the absence of bacteraemia during the neonatal period.

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Autores principales: Dennis Pägelow, Chintan Chhatbar, Andreas Beineke, Xiaokun Liu, Andreas Nerlich, Kira van Vorst, Manfred Rohde, Ulrich Kalinke, Reinhold Förster, Stephan Halle, Peter Valentin-Weigand, Mathias W. Hornef, Marcus Fulde
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/c08c113f11854074a92f5cc129f573b3
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spelling oai:doaj.org-article:c08c113f11854074a92f5cc129f573b32021-12-02T15:34:39ZThe olfactory epithelium as a port of entry in neonatal neurolisteriosis10.1038/s41467-018-06668-22041-1723https://doaj.org/article/c08c113f11854074a92f5cc129f573b32018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06668-2https://doaj.org/toc/2041-1723Listeria monocytogenes causes meningitis in newborns. Here, Pägelow et al. present a mouse model of neonatal cerebral listeriosis, and show that nasal inoculation, but not intragastric administration, leads to early brain infection in the absence of bacteraemia during the neonatal period.Dennis PägelowChintan ChhatbarAndreas BeinekeXiaokun LiuAndreas NerlichKira van VorstManfred RohdeUlrich KalinkeReinhold FörsterStephan HallePeter Valentin-WeigandMathias W. HornefMarcus FuldeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Dennis Pägelow
Chintan Chhatbar
Andreas Beineke
Xiaokun Liu
Andreas Nerlich
Kira van Vorst
Manfred Rohde
Ulrich Kalinke
Reinhold Förster
Stephan Halle
Peter Valentin-Weigand
Mathias W. Hornef
Marcus Fulde
The olfactory epithelium as a port of entry in neonatal neurolisteriosis
description Listeria monocytogenes causes meningitis in newborns. Here, Pägelow et al. present a mouse model of neonatal cerebral listeriosis, and show that nasal inoculation, but not intragastric administration, leads to early brain infection in the absence of bacteraemia during the neonatal period.
format article
author Dennis Pägelow
Chintan Chhatbar
Andreas Beineke
Xiaokun Liu
Andreas Nerlich
Kira van Vorst
Manfred Rohde
Ulrich Kalinke
Reinhold Förster
Stephan Halle
Peter Valentin-Weigand
Mathias W. Hornef
Marcus Fulde
author_facet Dennis Pägelow
Chintan Chhatbar
Andreas Beineke
Xiaokun Liu
Andreas Nerlich
Kira van Vorst
Manfred Rohde
Ulrich Kalinke
Reinhold Förster
Stephan Halle
Peter Valentin-Weigand
Mathias W. Hornef
Marcus Fulde
author_sort Dennis Pägelow
title The olfactory epithelium as a port of entry in neonatal neurolisteriosis
title_short The olfactory epithelium as a port of entry in neonatal neurolisteriosis
title_full The olfactory epithelium as a port of entry in neonatal neurolisteriosis
title_fullStr The olfactory epithelium as a port of entry in neonatal neurolisteriosis
title_full_unstemmed The olfactory epithelium as a port of entry in neonatal neurolisteriosis
title_sort olfactory epithelium as a port of entry in neonatal neurolisteriosis
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/c08c113f11854074a92f5cc129f573b3
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