The WHHERE coactivator complex is required for retinoic acid-dependent regulation of embryonic symmetry

Retinoic acid (RA) regulates the maintenance of somitogenesis symmetry. Here, the authors use a proteomic approach to identify a protein complex of Wdr5, Hdac1, Hdac2 that act together with RA and coactivator Rere/Atrophin2 and a histone methyltransferase Ehmt2 to regulate embryonic symmetry.

Guardado en:

Detalles Bibliográficos
Autores principales:	Gonçalo C. Vilhais-Neto, Marjorie Fournier, Jean-Luc Plassat, Mihaela E. Sardiu, Anita Saraf, Jean-Marie Garnier, Mitsuji Maruhashi, Laurence Florens, Michael P. Washburn, Olivier Pourquié
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c0924751d1f6443c91a937ddd9181ef0
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:c0924751d1f6443c91a937ddd9181ef0
record_format	dspace
spelling	oai:doaj.org-article:c0924751d1f6443c91a937ddd9181ef02021-12-02T15:38:41ZThe WHHERE coactivator complex is required for retinoic acid-dependent regulation of embryonic symmetry10.1038/s41467-017-00593-62041-1723https://doaj.org/article/c0924751d1f6443c91a937ddd9181ef02017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00593-6https://doaj.org/toc/2041-1723Retinoic acid (RA) regulates the maintenance of somitogenesis symmetry. Here, the authors use a proteomic approach to identify a protein complex of Wdr5, Hdac1, Hdac2 that act together with RA and coactivator Rere/Atrophin2 and a histone methyltransferase Ehmt2 to regulate embryonic symmetry.Gonçalo C. Vilhais-NetoMarjorie FournierJean-Luc PlassatMihaela E. SardiuAnita SarafJean-Marie GarnierMitsuji MaruhashiLaurence FlorensMichael P. WashburnOlivier PourquiéNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Gonçalo C. Vilhais-Neto Marjorie Fournier Jean-Luc Plassat Mihaela E. Sardiu Anita Saraf Jean-Marie Garnier Mitsuji Maruhashi Laurence Florens Michael P. Washburn Olivier Pourquié The WHHERE coactivator complex is required for retinoic acid-dependent regulation of embryonic symmetry
description	Retinoic acid (RA) regulates the maintenance of somitogenesis symmetry. Here, the authors use a proteomic approach to identify a protein complex of Wdr5, Hdac1, Hdac2 that act together with RA and coactivator Rere/Atrophin2 and a histone methyltransferase Ehmt2 to regulate embryonic symmetry.
format	article
author	Gonçalo C. Vilhais-Neto Marjorie Fournier Jean-Luc Plassat Mihaela E. Sardiu Anita Saraf Jean-Marie Garnier Mitsuji Maruhashi Laurence Florens Michael P. Washburn Olivier Pourquié
author_facet	Gonçalo C. Vilhais-Neto Marjorie Fournier Jean-Luc Plassat Mihaela E. Sardiu Anita Saraf Jean-Marie Garnier Mitsuji Maruhashi Laurence Florens Michael P. Washburn Olivier Pourquié
author_sort	Gonçalo C. Vilhais-Neto
title	The WHHERE coactivator complex is required for retinoic acid-dependent regulation of embryonic symmetry
title_short	The WHHERE coactivator complex is required for retinoic acid-dependent regulation of embryonic symmetry
title_full	The WHHERE coactivator complex is required for retinoic acid-dependent regulation of embryonic symmetry
title_fullStr	The WHHERE coactivator complex is required for retinoic acid-dependent regulation of embryonic symmetry
title_full_unstemmed	The WHHERE coactivator complex is required for retinoic acid-dependent regulation of embryonic symmetry
title_sort	whhere coactivator complex is required for retinoic acid-dependent regulation of embryonic symmetry
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/c0924751d1f6443c91a937ddd9181ef0
work_keys_str_mv	AT goncalocvilhaisneto thewhherecoactivatorcomplexisrequiredforretinoicaciddependentregulationofembryonicsymmetry AT marjoriefournier thewhherecoactivatorcomplexisrequiredforretinoicaciddependentregulationofembryonicsymmetry AT jeanlucplassat thewhherecoactivatorcomplexisrequiredforretinoicaciddependentregulationofembryonicsymmetry AT mihaelaesardiu thewhherecoactivatorcomplexisrequiredforretinoicaciddependentregulationofembryonicsymmetry AT anitasaraf thewhherecoactivatorcomplexisrequiredforretinoicaciddependentregulationofembryonicsymmetry AT jeanmariegarnier thewhherecoactivatorcomplexisrequiredforretinoicaciddependentregulationofembryonicsymmetry AT mitsujimaruhashi thewhherecoactivatorcomplexisrequiredforretinoicaciddependentregulationofembryonicsymmetry AT laurenceflorens thewhherecoactivatorcomplexisrequiredforretinoicaciddependentregulationofembryonicsymmetry AT michaelpwashburn thewhherecoactivatorcomplexisrequiredforretinoicaciddependentregulationofembryonicsymmetry AT olivierpourquie thewhherecoactivatorcomplexisrequiredforretinoicaciddependentregulationofembryonicsymmetry AT goncalocvilhaisneto whherecoactivatorcomplexisrequiredforretinoicaciddependentregulationofembryonicsymmetry AT marjoriefournier whherecoactivatorcomplexisrequiredforretinoicaciddependentregulationofembryonicsymmetry AT jeanlucplassat whherecoactivatorcomplexisrequiredforretinoicaciddependentregulationofembryonicsymmetry AT mihaelaesardiu whherecoactivatorcomplexisrequiredforretinoicaciddependentregulationofembryonicsymmetry AT anitasaraf whherecoactivatorcomplexisrequiredforretinoicaciddependentregulationofembryonicsymmetry AT jeanmariegarnier whherecoactivatorcomplexisrequiredforretinoicaciddependentregulationofembryonicsymmetry AT mitsujimaruhashi whherecoactivatorcomplexisrequiredforretinoicaciddependentregulationofembryonicsymmetry AT laurenceflorens whherecoactivatorcomplexisrequiredforretinoicaciddependentregulationofembryonicsymmetry AT michaelpwashburn whherecoactivatorcomplexisrequiredforretinoicaciddependentregulationofembryonicsymmetry AT olivierpourquie whherecoactivatorcomplexisrequiredforretinoicaciddependentregulationofembryonicsymmetry
_version_	1718386138210631680

The WHHERE coactivator complex is required for retinoic acid-dependent regulation of embryonic symmetry

Ejemplares similares