INPP4B protects from metabolic syndrome and associated disorders
Characterizing mice lacking Inositol Polyphosphate-4-Phosphatase Type II B (INPP4B), Zhang et al. discovered that SREBP1 signaling is activated in livers of Inpp4b −/− males leading to development of NAFLD and insulin resistance. When fed high fat diet, Inpp4b −/− males develop type II diabetes, inf...
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Autores principales: | Manqi Zhang, Yasemin Ceyhan, Elena M. Kaftanovskaya, Judy L. Vasquez, Jean Vacher, Filip K. Knop, Lubov Nathanson, Alexander I. Agoulnik, Michael M. Ittmann, Irina U. Agoulnik |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/c0aa0d8467f04c44b12025eeec6637fa |
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