Androgens contribute to sex differences in myocardial remodeling under pressure overload by a mechanism involving TGF-β.

<h4>Background</h4>In clinical studies, myocardial remodeling in aortic valve stenosis appears to be more favorable in women than in men, even after menopause. In the present study, we assessed whether circulating androgens contribute to a less favorable myocardial remodeling under press...

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Autores principales: Cecilia Montalvo, Ana V Villar, David Merino, Raquel García, Miguel Ares, Miguel Llano, Manuel Cobo, María A Hurlé, J Francisco Nistal
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/c0ae32a71e434f96838c3c000749c75f
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