Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system

Genome-wide association studies have identified multiple loci for resting heart rate (HR) but the genetic factors associated with HR increase during and HR recovery after exercise are less well studied. Here, the authors examine both traits in a two-stage GWAS design in up to 67,257 individuals from...

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Autores principales: Julia Ramírez, Stefan van Duijvenboden, Ioanna Ntalla, Borbala Mifsud, Helen R Warren, Evan Tzanis, Michele Orini, Andrew Tinker, Pier D. Lambiase, Patricia B. Munroe
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/c0b8087cae154c7b97a4bbad5718ef4b
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spelling oai:doaj.org-article:c0b8087cae154c7b97a4bbad5718ef4b2021-12-02T16:49:18ZThirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system10.1038/s41467-018-04148-12041-1723https://doaj.org/article/c0b8087cae154c7b97a4bbad5718ef4b2018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04148-1https://doaj.org/toc/2041-1723Genome-wide association studies have identified multiple loci for resting heart rate (HR) but the genetic factors associated with HR increase during and HR recovery after exercise are less well studied. Here, the authors examine both traits in a two-stage GWAS design in up to 67,257 individuals from UK Biobank.Julia RamírezStefan van DuijvenbodenIoanna NtallaBorbala MifsudHelen R WarrenEvan TzanisMichele OriniAndrew TinkerPier D. LambiasePatricia B. MunroeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Julia Ramírez
Stefan van Duijvenboden
Ioanna Ntalla
Borbala Mifsud
Helen R Warren
Evan Tzanis
Michele Orini
Andrew Tinker
Pier D. Lambiase
Patricia B. Munroe
Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system
description Genome-wide association studies have identified multiple loci for resting heart rate (HR) but the genetic factors associated with HR increase during and HR recovery after exercise are less well studied. Here, the authors examine both traits in a two-stage GWAS design in up to 67,257 individuals from UK Biobank.
format article
author Julia Ramírez
Stefan van Duijvenboden
Ioanna Ntalla
Borbala Mifsud
Helen R Warren
Evan Tzanis
Michele Orini
Andrew Tinker
Pier D. Lambiase
Patricia B. Munroe
author_facet Julia Ramírez
Stefan van Duijvenboden
Ioanna Ntalla
Borbala Mifsud
Helen R Warren
Evan Tzanis
Michele Orini
Andrew Tinker
Pier D. Lambiase
Patricia B. Munroe
author_sort Julia Ramírez
title Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system
title_short Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system
title_full Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system
title_fullStr Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system
title_full_unstemmed Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system
title_sort thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/c0b8087cae154c7b97a4bbad5718ef4b
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AT micheleorini thirtylociidentifiedforheartrateresponsetoexerciseandrecoveryimplicateautonomicnervoussystem
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