Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system
Genome-wide association studies have identified multiple loci for resting heart rate (HR) but the genetic factors associated with HR increase during and HR recovery after exercise are less well studied. Here, the authors examine both traits in a two-stage GWAS design in up to 67,257 individuals from...
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Nature Portfolio
2018
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oai:doaj.org-article:c0b8087cae154c7b97a4bbad5718ef4b2021-12-02T16:49:18ZThirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system10.1038/s41467-018-04148-12041-1723https://doaj.org/article/c0b8087cae154c7b97a4bbad5718ef4b2018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04148-1https://doaj.org/toc/2041-1723Genome-wide association studies have identified multiple loci for resting heart rate (HR) but the genetic factors associated with HR increase during and HR recovery after exercise are less well studied. Here, the authors examine both traits in a two-stage GWAS design in up to 67,257 individuals from UK Biobank.Julia RamírezStefan van DuijvenbodenIoanna NtallaBorbala MifsudHelen R WarrenEvan TzanisMichele OriniAndrew TinkerPier D. LambiasePatricia B. MunroeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018) |
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Science Q Julia Ramírez Stefan van Duijvenboden Ioanna Ntalla Borbala Mifsud Helen R Warren Evan Tzanis Michele Orini Andrew Tinker Pier D. Lambiase Patricia B. Munroe Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system |
description |
Genome-wide association studies have identified multiple loci for resting heart rate (HR) but the genetic factors associated with HR increase during and HR recovery after exercise are less well studied. Here, the authors examine both traits in a two-stage GWAS design in up to 67,257 individuals from UK Biobank. |
format |
article |
author |
Julia Ramírez Stefan van Duijvenboden Ioanna Ntalla Borbala Mifsud Helen R Warren Evan Tzanis Michele Orini Andrew Tinker Pier D. Lambiase Patricia B. Munroe |
author_facet |
Julia Ramírez Stefan van Duijvenboden Ioanna Ntalla Borbala Mifsud Helen R Warren Evan Tzanis Michele Orini Andrew Tinker Pier D. Lambiase Patricia B. Munroe |
author_sort |
Julia Ramírez |
title |
Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system |
title_short |
Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system |
title_full |
Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system |
title_fullStr |
Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system |
title_full_unstemmed |
Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system |
title_sort |
thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/c0b8087cae154c7b97a4bbad5718ef4b |
work_keys_str_mv |
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1718383360060948480 |