Low-Carbohydrate Diet among Children with Type 1 Diabetes: A Multi-Center Study

Aims/hypothesis: The proportion of children with type 1 diabetes (T1D) who have experience with low-carbohydrate diet (LCD) is unknown. Our goal was to map the frequency of LCD among children with T1D and to describe their clinical and laboratory data. Methods: Caregivers of 1040 children with T1D f...

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Autores principales:	Vit Neuman, Lukas Plachy, Stepanka Pruhova, Stanislava Kolouskova, Lenka Petruzelkova, Barbora Obermannova, Jana Vyzralkova, Petra Konecna, Jan Vosahlo, Martina Romanova, Marketa Pavlikova, Zdenek Sumnik
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	low-carbohydrate diet time in range type 1 diabetes Nutrition. Foods and food supply TX341-641
Acceso en línea:	https://doaj.org/article/c0c18c0ed2c442a9a1898c79b0910309
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spelling	oai:doaj.org-article:c0c18c0ed2c442a9a1898c79b09103092021-11-25T18:35:07ZLow-Carbohydrate Diet among Children with Type 1 Diabetes: A Multi-Center Study10.3390/nu131139032072-6643https://doaj.org/article/c0c18c0ed2c442a9a1898c79b09103092021-10-01T00:00:00Zhttps://www.mdpi.com/2072-6643/13/11/3903https://doaj.org/toc/2072-6643Aims/hypothesis: The proportion of children with type 1 diabetes (T1D) who have experience with low-carbohydrate diet (LCD) is unknown. Our goal was to map the frequency of LCD among children with T1D and to describe their clinical and laboratory data. Methods: Caregivers of 1040 children with T1D from three centers were addressed with a structured questionnaire regarding the children’s carbohydrate intake and experience with LCD (daily energy intake from carbohydrates below 26% of age-recommended values). The subjects currently on LCD were compared to a group of non-LCD respondents matched to age, T1D duration, sex, type and center of treatment. Results: A total of 624/1040 (60%) of the subjects completed the survey. A total of 242/624 (39%) subjects reported experience with voluntary carbohydrate restriction with 36/624 (5.8%) subjects currently following the LCD. The LCD group had similar HbA1c (45 vs. 49.5, <i>p</i> = 0.11), lower average glycemia (7.0 vs. 7.9, <i>p</i> = 0.02), higher time in range (74 vs. 67%, <i>p</i> = 0.02), lower time in hyperglycemia >10 mmol/L (17 vs. 20%, <i>p</i> = 0.04), tendency to more time in hypoglycemia <3.9 mmol/L(8 vs. 5%, <i>p</i> = 0.05) and lower systolic blood pressure percentile (43 vs. 74, <i>p</i> = 0.03). The groups did not differ in their lipid profile nor in current body height, weight or BMI. The LCD was mostly initiated by the parents or the subjects themselves and only 39% of the families consulted their decision with the diabetologist. Conclusions/interpretation: Low carbohydrate diet is not scarce in children with T1D and is associated with modestly better disease control. At the same time, caution should be applied as it showed a tendency toward more frequent hypoglycemia.Vit NeumanLukas PlachyStepanka PruhovaStanislava KolouskovaLenka PetruzelkovaBarbora ObermannovaJana VyzralkovaPetra KonecnaJan VosahloMartina RomanovaMarketa PavlikovaZdenek SumnikMDPI AGarticlelow-carbohydrate diettime in rangetype 1 diabetesNutrition. Foods and food supplyTX341-641ENNutrients, Vol 13, Iss 3903, p 3903 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	low-carbohydrate diet time in range type 1 diabetes Nutrition. Foods and food supply TX341-641
spellingShingle	low-carbohydrate diet time in range type 1 diabetes Nutrition. Foods and food supply TX341-641 Vit Neuman Lukas Plachy Stepanka Pruhova Stanislava Kolouskova Lenka Petruzelkova Barbora Obermannova Jana Vyzralkova Petra Konecna Jan Vosahlo Martina Romanova Marketa Pavlikova Zdenek Sumnik Low-Carbohydrate Diet among Children with Type 1 Diabetes: A Multi-Center Study
description	Aims/hypothesis: The proportion of children with type 1 diabetes (T1D) who have experience with low-carbohydrate diet (LCD) is unknown. Our goal was to map the frequency of LCD among children with T1D and to describe their clinical and laboratory data. Methods: Caregivers of 1040 children with T1D from three centers were addressed with a structured questionnaire regarding the children’s carbohydrate intake and experience with LCD (daily energy intake from carbohydrates below 26% of age-recommended values). The subjects currently on LCD were compared to a group of non-LCD respondents matched to age, T1D duration, sex, type and center of treatment. Results: A total of 624/1040 (60%) of the subjects completed the survey. A total of 242/624 (39%) subjects reported experience with voluntary carbohydrate restriction with 36/624 (5.8%) subjects currently following the LCD. The LCD group had similar HbA1c (45 vs. 49.5, <i>p</i> = 0.11), lower average glycemia (7.0 vs. 7.9, <i>p</i> = 0.02), higher time in range (74 vs. 67%, <i>p</i> = 0.02), lower time in hyperglycemia >10 mmol/L (17 vs. 20%, <i>p</i> = 0.04), tendency to more time in hypoglycemia <3.9 mmol/L(8 vs. 5%, <i>p</i> = 0.05) and lower systolic blood pressure percentile (43 vs. 74, <i>p</i> = 0.03). The groups did not differ in their lipid profile nor in current body height, weight or BMI. The LCD was mostly initiated by the parents or the subjects themselves and only 39% of the families consulted their decision with the diabetologist. Conclusions/interpretation: Low carbohydrate diet is not scarce in children with T1D and is associated with modestly better disease control. At the same time, caution should be applied as it showed a tendency toward more frequent hypoglycemia.
format	article
author	Vit Neuman Lukas Plachy Stepanka Pruhova Stanislava Kolouskova Lenka Petruzelkova Barbora Obermannova Jana Vyzralkova Petra Konecna Jan Vosahlo Martina Romanova Marketa Pavlikova Zdenek Sumnik
author_facet	Vit Neuman Lukas Plachy Stepanka Pruhova Stanislava Kolouskova Lenka Petruzelkova Barbora Obermannova Jana Vyzralkova Petra Konecna Jan Vosahlo Martina Romanova Marketa Pavlikova Zdenek Sumnik
author_sort	Vit Neuman
title	Low-Carbohydrate Diet among Children with Type 1 Diabetes: A Multi-Center Study
title_short	Low-Carbohydrate Diet among Children with Type 1 Diabetes: A Multi-Center Study
title_full	Low-Carbohydrate Diet among Children with Type 1 Diabetes: A Multi-Center Study
title_fullStr	Low-Carbohydrate Diet among Children with Type 1 Diabetes: A Multi-Center Study
title_full_unstemmed	Low-Carbohydrate Diet among Children with Type 1 Diabetes: A Multi-Center Study
title_sort	low-carbohydrate diet among children with type 1 diabetes: a multi-center study
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/c0c18c0ed2c442a9a1898c79b0910309
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Low-Carbohydrate Diet among Children with Type 1 Diabetes: A Multi-Center Study

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