Functional characterization of a bioengineered liver after heterotopic implantation in pigs

Anderson et al. demonstrate a method for seeding and engrafting primary porcine hepatocytes into a bioengineered liver (BEL) scaffold previously reendothelialized with HUVECs. This study constitutes an important advance in the effort to generate transplantable livers of a clinically relevant size fo...

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Autores principales:	Brett D. Anderson, Erek D. Nelson, DongJin Joo, Bruce P. Amiot, Aleksandr A. Katane, Alyssa Mendenhall, Benjamin G. Steiner, Aron R. Stumbras, Victoria L. Nelson, R. Noelle Palumbo, Thomas W. Gilbert, Dominique S. Davidow, Jeffrey J. Ross, Scott L. Nyberg
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/c0c41e41b8204756bab603753cae52e2
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spelling	oai:doaj.org-article:c0c41e41b8204756bab603753cae52e22021-12-02T18:36:11ZFunctional characterization of a bioengineered liver after heterotopic implantation in pigs10.1038/s42003-021-02665-22399-3642https://doaj.org/article/c0c41e41b8204756bab603753cae52e22021-10-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02665-2https://doaj.org/toc/2399-3642Anderson et al. demonstrate a method for seeding and engrafting primary porcine hepatocytes into a bioengineered liver (BEL) scaffold previously reendothelialized with HUVECs. This study constitutes an important advance in the effort to generate transplantable livers of a clinically relevant size for humans.Brett D. AndersonErek D. NelsonDongJin JooBruce P. AmiotAleksandr A. KataneAlyssa MendenhallBenjamin G. SteinerAron R. StumbrasVictoria L. NelsonR. Noelle PalumboThomas W. GilbertDominique S. DavidowJeffrey J. RossScott L. NybergNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Brett D. Anderson Erek D. Nelson DongJin Joo Bruce P. Amiot Aleksandr A. Katane Alyssa Mendenhall Benjamin G. Steiner Aron R. Stumbras Victoria L. Nelson R. Noelle Palumbo Thomas W. Gilbert Dominique S. Davidow Jeffrey J. Ross Scott L. Nyberg Functional characterization of a bioengineered liver after heterotopic implantation in pigs
description	Anderson et al. demonstrate a method for seeding and engrafting primary porcine hepatocytes into a bioengineered liver (BEL) scaffold previously reendothelialized with HUVECs. This study constitutes an important advance in the effort to generate transplantable livers of a clinically relevant size for humans.
format	article
author	Brett D. Anderson Erek D. Nelson DongJin Joo Bruce P. Amiot Aleksandr A. Katane Alyssa Mendenhall Benjamin G. Steiner Aron R. Stumbras Victoria L. Nelson R. Noelle Palumbo Thomas W. Gilbert Dominique S. Davidow Jeffrey J. Ross Scott L. Nyberg
author_facet	Brett D. Anderson Erek D. Nelson DongJin Joo Bruce P. Amiot Aleksandr A. Katane Alyssa Mendenhall Benjamin G. Steiner Aron R. Stumbras Victoria L. Nelson R. Noelle Palumbo Thomas W. Gilbert Dominique S. Davidow Jeffrey J. Ross Scott L. Nyberg
author_sort	Brett D. Anderson
title	Functional characterization of a bioengineered liver after heterotopic implantation in pigs
title_short	Functional characterization of a bioengineered liver after heterotopic implantation in pigs
title_full	Functional characterization of a bioengineered liver after heterotopic implantation in pigs
title_fullStr	Functional characterization of a bioengineered liver after heterotopic implantation in pigs
title_full_unstemmed	Functional characterization of a bioengineered liver after heterotopic implantation in pigs
title_sort	functional characterization of a bioengineered liver after heterotopic implantation in pigs
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/c0c41e41b8204756bab603753cae52e2
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Functional characterization of a bioengineered liver after heterotopic implantation in pigs

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