The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin

RepID has previously been shown to promote origin firing. Here the authors reveal that RepID regulates replication origins via the recruitment of the CRL4 complex, and prevents re-initiation and unscheduled DNA replication.

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Autores principales:	Sang-Min Jang, Ya Zhang, Koichi Utani, Haiqing Fu, Christophe E. Redon, Anna B. Marks, Owen K. Smith, Catherine J. Redmond, Adrian M. Baris, Danielle A. Tulchinsky, Mirit I. Aladjem
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c0caf93747014adfa69d1bd61d2bb88a
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spelling	oai:doaj.org-article:c0caf93747014adfa69d1bd61d2bb88a2021-12-02T15:34:20ZThe replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin10.1038/s41467-018-05177-62041-1723https://doaj.org/article/c0caf93747014adfa69d1bd61d2bb88a2018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05177-6https://doaj.org/toc/2041-1723RepID has previously been shown to promote origin firing. Here the authors reveal that RepID regulates replication origins via the recruitment of the CRL4 complex, and prevents re-initiation and unscheduled DNA replication.Sang-Min JangYa ZhangKoichi UtaniHaiqing FuChristophe E. RedonAnna B. MarksOwen K. SmithCatherine J. RedmondAdrian M. BarisDanielle A. TulchinskyMirit I. AladjemNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sang-Min Jang Ya Zhang Koichi Utani Haiqing Fu Christophe E. Redon Anna B. Marks Owen K. Smith Catherine J. Redmond Adrian M. Baris Danielle A. Tulchinsky Mirit I. Aladjem The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin
description	RepID has previously been shown to promote origin firing. Here the authors reveal that RepID regulates replication origins via the recruitment of the CRL4 complex, and prevents re-initiation and unscheduled DNA replication.
format	article
author	Sang-Min Jang Ya Zhang Koichi Utani Haiqing Fu Christophe E. Redon Anna B. Marks Owen K. Smith Catherine J. Redmond Adrian M. Baris Danielle A. Tulchinsky Mirit I. Aladjem
author_facet	Sang-Min Jang Ya Zhang Koichi Utani Haiqing Fu Christophe E. Redon Anna B. Marks Owen K. Smith Catherine J. Redmond Adrian M. Baris Danielle A. Tulchinsky Mirit I. Aladjem
author_sort	Sang-Min Jang
title	The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin
title_short	The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin
title_full	The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin
title_fullStr	The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin
title_full_unstemmed	The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin
title_sort	replication initiation determinant protein (repid) modulates replication by recruiting cul4 to chromatin
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/c0caf93747014adfa69d1bd61d2bb88a
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The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin

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