Association between COVID-19 Vaccine Side Effects and Body Mass Index in Spain

COVID-19 vaccines have shown high efficacy, with most side effects being mild–moderate and more frequently reported by females and people at younger ages. Since no studies have assessed the impact that weight status could have on the reported adverse reactions, we aim to study the association betwee...

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Autores principales:	Isabel Iguacel, Aurelio Luna Maldonado, Aurelio Luna Ruiz-Cabello, Marta Casaus, Luis Alberto Moreno, Begoña Martínez-Jarreta
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	SARS CoV-2 vaccination overweight obesity vaccine adverse events Medicine R
Acceso en línea:	https://doaj.org/article/c0de24d36791409583c373aa57a3377a
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spelling	oai:doaj.org-article:c0de24d36791409583c373aa57a3377a2021-11-25T19:11:18ZAssociation between COVID-19 Vaccine Side Effects and Body Mass Index in Spain10.3390/vaccines91113212076-393Xhttps://doaj.org/article/c0de24d36791409583c373aa57a3377a2021-11-01T00:00:00Zhttps://www.mdpi.com/2076-393X/9/11/1321https://doaj.org/toc/2076-393XCOVID-19 vaccines have shown high efficacy, with most side effects being mild–moderate and more frequently reported by females and people at younger ages. Since no studies have assessed the impact that weight status could have on the reported adverse reactions, we aim to study the association between weight status and reported side effects. We included data on 2136 adults from an online survey conducted from 6 May to 9 June 2021. The questionnaire was filled in by participants over Google forms. Generalized Linear Mixed Models were used. A higher risk of presenting fever ≥38°, vomiting, diarrhea and chills was found in those with a non-overweight status compared to those overweight after adjusting for age, sex, education, medication to prevent/relieve post-vaccination effects and vaccine administered. When adjusting, most of the significant effects, in the association between side effects of the COVID-19 vaccine and weight status, did not remain significant. In conclusion, a non-overweight status was associated with a higher risk of presenting fever ≥38°, vomiting, diarrhea and chills compared to those overweight. Nevertheless, most of the reported side effects to COVID-19 vaccine were not associated with a higher risk of presenting more adverse effects, and individual differences were determined by sex and age.Isabel IguacelAurelio Luna MaldonadoAurelio Luna Ruiz-CabelloMarta CasausLuis Alberto MorenoBegoña Martínez-JarretaMDPI AGarticleSARS CoV-2vaccinationoverweightobesityvaccine adverse eventsMedicineRENVaccines, Vol 9, Iss 1321, p 1321 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	SARS CoV-2 vaccination overweight obesity vaccine adverse events Medicine R
spellingShingle	SARS CoV-2 vaccination overweight obesity vaccine adverse events Medicine R Isabel Iguacel Aurelio Luna Maldonado Aurelio Luna Ruiz-Cabello Marta Casaus Luis Alberto Moreno Begoña Martínez-Jarreta Association between COVID-19 Vaccine Side Effects and Body Mass Index in Spain
description	COVID-19 vaccines have shown high efficacy, with most side effects being mild–moderate and more frequently reported by females and people at younger ages. Since no studies have assessed the impact that weight status could have on the reported adverse reactions, we aim to study the association between weight status and reported side effects. We included data on 2136 adults from an online survey conducted from 6 May to 9 June 2021. The questionnaire was filled in by participants over Google forms. Generalized Linear Mixed Models were used. A higher risk of presenting fever ≥38°, vomiting, diarrhea and chills was found in those with a non-overweight status compared to those overweight after adjusting for age, sex, education, medication to prevent/relieve post-vaccination effects and vaccine administered. When adjusting, most of the significant effects, in the association between side effects of the COVID-19 vaccine and weight status, did not remain significant. In conclusion, a non-overweight status was associated with a higher risk of presenting fever ≥38°, vomiting, diarrhea and chills compared to those overweight. Nevertheless, most of the reported side effects to COVID-19 vaccine were not associated with a higher risk of presenting more adverse effects, and individual differences were determined by sex and age.
format	article
author	Isabel Iguacel Aurelio Luna Maldonado Aurelio Luna Ruiz-Cabello Marta Casaus Luis Alberto Moreno Begoña Martínez-Jarreta
author_facet	Isabel Iguacel Aurelio Luna Maldonado Aurelio Luna Ruiz-Cabello Marta Casaus Luis Alberto Moreno Begoña Martínez-Jarreta
author_sort	Isabel Iguacel
title	Association between COVID-19 Vaccine Side Effects and Body Mass Index in Spain
title_short	Association between COVID-19 Vaccine Side Effects and Body Mass Index in Spain
title_full	Association between COVID-19 Vaccine Side Effects and Body Mass Index in Spain
title_fullStr	Association between COVID-19 Vaccine Side Effects and Body Mass Index in Spain
title_full_unstemmed	Association between COVID-19 Vaccine Side Effects and Body Mass Index in Spain
title_sort	association between covid-19 vaccine side effects and body mass index in spain
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/c0de24d36791409583c373aa57a3377a
work_keys_str_mv	AT isabeliguacel associationbetweencovid19vaccinesideeffectsandbodymassindexinspain AT aureliolunamaldonado associationbetweencovid19vaccinesideeffectsandbodymassindexinspain AT aureliolunaruizcabello associationbetweencovid19vaccinesideeffectsandbodymassindexinspain AT martacasaus associationbetweencovid19vaccinesideeffectsandbodymassindexinspain AT luisalbertomoreno associationbetweencovid19vaccinesideeffectsandbodymassindexinspain AT begonamartinezjarreta associationbetweencovid19vaccinesideeffectsandbodymassindexinspain
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Association between COVID-19 Vaccine Side Effects and Body Mass Index in Spain

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