Protective Effect of <i>Siegesbeckia orientalis</i> on Pancreatic β-Cells under High Glucose-Induced Glucotoxicity

Protective Effect of <i>Siegesbeckia orientalis</i> on Pancreatic β-Cells under High Glucose-Induced Glucotoxicity

The glucotoxicity caused by long-term exposure of β-cells to high glucose (HG) conditions may lead to the generation of more reactive oxygen species (ROS), reduce the activity of antioxidant enzymes, cause cell damage and apoptosis, and induce insulin secretion dysfunction. <i>Siegesbeckia ori...

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Bibliographic Details
Main Authors: Chi-Chang Chang, Jer-Yiing Houng, Shih-Wei Wang, Chin-Feng Hsuan, Yung-Chuan Lu, Tzu-Hsien Chang, Ya-Ling Chen
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
<i>Siegesbeckia orientalis</i>
pancreatic β-cells
glucotoxicity
oxidative stress
cell proliferation
antioxidant enzyme activity
Technology
T
Engineering (General). Civil engineering (General)
TA1-2040
Biology (General)
QH301-705.5
Physics
QC1-999
Chemistry
QD1-999
Online Access:https://doaj.org/article/c0e3920f7b6f444695973db35132613f
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https://doaj.org/article/c0e3920f7b6f444695973db35132613f

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