Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis
Changes in global histone trimethylation have been linked to embryonic but not adult stem cell plasticity. Here, Lee et al. find H3 K4/K9/K27me3 levels actively reduced in adult mouse skin and hair follicle stem cells during quiescence (catagen) and link this to active bone morphogen protein signall...
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Nature Portfolio
2016
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oai:doaj.org-article:c0f2eaaa2ce7421fa4a9eca52ccf4ad02021-12-02T14:39:30ZSignalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis10.1038/ncomms112782041-1723https://doaj.org/article/c0f2eaaa2ce7421fa4a9eca52ccf4ad02016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11278https://doaj.org/toc/2041-1723Changes in global histone trimethylation have been linked to embryonic but not adult stem cell plasticity. Here, Lee et al. find H3 K4/K9/K27me3 levels actively reduced in adult mouse skin and hair follicle stem cells during quiescence (catagen) and link this to active bone morphogen protein signalling.Jayhun LeeSangjo KangKarin C. LiljaKeegan J. ColletierCornelia Johanna Franziska ScheitzYing V. ZhangTudorita TumbarNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016) |
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Science Q Jayhun Lee Sangjo Kang Karin C. Lilja Keegan J. Colletier Cornelia Johanna Franziska Scheitz Ying V. Zhang Tudorita Tumbar Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis |
description |
Changes in global histone trimethylation have been linked to embryonic but not adult stem cell plasticity. Here, Lee et al. find H3 K4/K9/K27me3 levels actively reduced in adult mouse skin and hair follicle stem cells during quiescence (catagen) and link this to active bone morphogen protein signalling. |
format |
article |
author |
Jayhun Lee Sangjo Kang Karin C. Lilja Keegan J. Colletier Cornelia Johanna Franziska Scheitz Ying V. Zhang Tudorita Tumbar |
author_facet |
Jayhun Lee Sangjo Kang Karin C. Lilja Keegan J. Colletier Cornelia Johanna Franziska Scheitz Ying V. Zhang Tudorita Tumbar |
author_sort |
Jayhun Lee |
title |
Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis |
title_short |
Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis |
title_full |
Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis |
title_fullStr |
Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis |
title_full_unstemmed |
Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis |
title_sort |
signalling couples hair follicle stem cell quiescence with reduced histone h3 k4/k9/k27me3 for proper tissue homeostasis |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/c0f2eaaa2ce7421fa4a9eca52ccf4ad0 |
work_keys_str_mv |
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