Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis

Changes in global histone trimethylation have been linked to embryonic but not adult stem cell plasticity. Here, Lee et al. find H3 K4/K9/K27me3 levels actively reduced in adult mouse skin and hair follicle stem cells during quiescence (catagen) and link this to active bone morphogen protein signall...

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Autores principales: Jayhun Lee, Sangjo Kang, Karin C. Lilja, Keegan J. Colletier, Cornelia Johanna Franziska Scheitz, Ying V. Zhang, Tudorita Tumbar
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/c0f2eaaa2ce7421fa4a9eca52ccf4ad0
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spelling oai:doaj.org-article:c0f2eaaa2ce7421fa4a9eca52ccf4ad02021-12-02T14:39:30ZSignalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis10.1038/ncomms112782041-1723https://doaj.org/article/c0f2eaaa2ce7421fa4a9eca52ccf4ad02016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11278https://doaj.org/toc/2041-1723Changes in global histone trimethylation have been linked to embryonic but not adult stem cell plasticity. Here, Lee et al. find H3 K4/K9/K27me3 levels actively reduced in adult mouse skin and hair follicle stem cells during quiescence (catagen) and link this to active bone morphogen protein signalling.Jayhun LeeSangjo KangKarin C. LiljaKeegan J. ColletierCornelia Johanna Franziska ScheitzYing V. ZhangTudorita TumbarNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jayhun Lee
Sangjo Kang
Karin C. Lilja
Keegan J. Colletier
Cornelia Johanna Franziska Scheitz
Ying V. Zhang
Tudorita Tumbar
Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis
description Changes in global histone trimethylation have been linked to embryonic but not adult stem cell plasticity. Here, Lee et al. find H3 K4/K9/K27me3 levels actively reduced in adult mouse skin and hair follicle stem cells during quiescence (catagen) and link this to active bone morphogen protein signalling.
format article
author Jayhun Lee
Sangjo Kang
Karin C. Lilja
Keegan J. Colletier
Cornelia Johanna Franziska Scheitz
Ying V. Zhang
Tudorita Tumbar
author_facet Jayhun Lee
Sangjo Kang
Karin C. Lilja
Keegan J. Colletier
Cornelia Johanna Franziska Scheitz
Ying V. Zhang
Tudorita Tumbar
author_sort Jayhun Lee
title Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis
title_short Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis
title_full Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis
title_fullStr Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis
title_full_unstemmed Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis
title_sort signalling couples hair follicle stem cell quiescence with reduced histone h3 k4/k9/k27me3 for proper tissue homeostasis
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/c0f2eaaa2ce7421fa4a9eca52ccf4ad0
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