Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis

Changes in global histone trimethylation have been linked to embryonic but not adult stem cell plasticity. Here, Lee et al. find H3 K4/K9/K27me3 levels actively reduced in adult mouse skin and hair follicle stem cells during quiescence (catagen) and link this to active bone morphogen protein signall...

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Autores principales: Jayhun Lee, Sangjo Kang, Karin C. Lilja, Keegan J. Colletier, Cornelia Johanna Franziska Scheitz, Ying V. Zhang, Tudorita Tumbar
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/c0f2eaaa2ce7421fa4a9eca52ccf4ad0
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