Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis
Changes in global histone trimethylation have been linked to embryonic but not adult stem cell plasticity. Here, Lee et al. find H3 K4/K9/K27me3 levels actively reduced in adult mouse skin and hair follicle stem cells during quiescence (catagen) and link this to active bone morphogen protein signall...
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Auteurs principaux: | Jayhun Lee, Sangjo Kang, Karin C. Lilja, Keegan J. Colletier, Cornelia Johanna Franziska Scheitz, Ying V. Zhang, Tudorita Tumbar |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2016
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Accès en ligne: | https://doaj.org/article/c0f2eaaa2ce7421fa4a9eca52ccf4ad0 |
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