Intranasal vaccine from whole Leishmania donovani antigens provides protection and induces specific immune response against visceral leishmaniasis.

Visceral leishmaniasis is a protozoan disease associated with high fatality rate in developing countries. Although the drug pipeline is constantly improving, available treatments are costly and live-threatening side effects are not uncommon. Moreover, an approved vaccine against human leishmaniasis...

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Autores principales: Doumet Georges Helou, Aurélie Mauras, François Fasquelle, Juliane Sousa Lanza, Philippe M Loiseau, Didier Betbeder, Sandrine Cojean
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/c0f3e4d4ef4340d0a21442226aa11271
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