Understanding genetic risk factors for common side effects of antidepressant medications

Campos et al. study the genetic aetiology of antidepressant side effects. Using data from the Australian Genetics of Depression study, the authors show that polygenic risk scores for traits such as BMI, insomnia and headaches have a shared genetic basis with side effects to commonly used antidepress...

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Autores principales: Adrian I. Campos, Aoibhe Mulcahy, Jackson G. Thorp, Naomi R. Wray, Enda M. Byrne, Penelope A. Lind, Sarah E. Medland, Nicholas G. Martin, Ian B. Hickie, Miguel E. Rentería
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/c0fde98500264eae890623636a92ff20
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spelling oai:doaj.org-article:c0fde98500264eae890623636a92ff202021-11-14T12:16:56ZUnderstanding genetic risk factors for common side effects of antidepressant medications10.1038/s43856-021-00046-82730-664Xhttps://doaj.org/article/c0fde98500264eae890623636a92ff202021-11-01T00:00:00Zhttps://doi.org/10.1038/s43856-021-00046-8https://doaj.org/toc/2730-664XCampos et al. study the genetic aetiology of antidepressant side effects. Using data from the Australian Genetics of Depression study, the authors show that polygenic risk scores for traits such as BMI, insomnia and headaches have a shared genetic basis with side effects to commonly used antidepressant drugs.Adrian I. CamposAoibhe MulcahyJackson G. ThorpNaomi R. WrayEnda M. ByrnePenelope A. LindSarah E. MedlandNicholas G. MartinIan B. HickieMiguel E. RenteríaNature PortfolioarticleMedicineRENCommunications Medicine, Vol 1, Iss 1, Pp 1-10 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
spellingShingle Medicine
R
Adrian I. Campos
Aoibhe Mulcahy
Jackson G. Thorp
Naomi R. Wray
Enda M. Byrne
Penelope A. Lind
Sarah E. Medland
Nicholas G. Martin
Ian B. Hickie
Miguel E. Rentería
Understanding genetic risk factors for common side effects of antidepressant medications
description Campos et al. study the genetic aetiology of antidepressant side effects. Using data from the Australian Genetics of Depression study, the authors show that polygenic risk scores for traits such as BMI, insomnia and headaches have a shared genetic basis with side effects to commonly used antidepressant drugs.
format article
author Adrian I. Campos
Aoibhe Mulcahy
Jackson G. Thorp
Naomi R. Wray
Enda M. Byrne
Penelope A. Lind
Sarah E. Medland
Nicholas G. Martin
Ian B. Hickie
Miguel E. Rentería
author_facet Adrian I. Campos
Aoibhe Mulcahy
Jackson G. Thorp
Naomi R. Wray
Enda M. Byrne
Penelope A. Lind
Sarah E. Medland
Nicholas G. Martin
Ian B. Hickie
Miguel E. Rentería
author_sort Adrian I. Campos
title Understanding genetic risk factors for common side effects of antidepressant medications
title_short Understanding genetic risk factors for common side effects of antidepressant medications
title_full Understanding genetic risk factors for common side effects of antidepressant medications
title_fullStr Understanding genetic risk factors for common side effects of antidepressant medications
title_full_unstemmed Understanding genetic risk factors for common side effects of antidepressant medications
title_sort understanding genetic risk factors for common side effects of antidepressant medications
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/c0fde98500264eae890623636a92ff20
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