Peroxisome proliferator-activated receptor (PPAR) γ and PPARα agonists modulate mitochondrial fusion-fission dynamics: relevance to reactive oxygen species (ROS)-related neurodegenerative disorders?

Recent studies showed that the activation of the retinoid X receptor, which dimerizes with peroxisome proliferator-activated receptors (PPARs), leads to an enhanced clearance of Aβ from the brain of transgenic mice model of Alzheimer's disease (AD), because an increased expression of apolipopro...

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Bibliographic Details
Main Authors: Juan M Zolezzi, Carmen Silva-Alvarez, Daniela Ordenes, Juan A Godoy, Francisco J Carvajal, Manuel J Santos, Nibaldo C Inestrosa
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
R
Q
Online Access:https://doaj.org/article/c102996b2ec64f1e8b8de5ea23a09591
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