Arterial Parameters in Type-2 Diabetes and Healthy Subjects by using Impedance Plethysmography: A Case-control Study
Introduction: A reduced blood supply to lower limb, due to arterial disease, is a common cause of foot ulceration in patients with Diabetes Mellitus (DM). Impedance Plethysmography (IPG) is based on the measurement of changes in the electrical resistance (impedance) caused by blood volume change...
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| Autores principales: | , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
JCDR Research and Publications Private Limited
2021
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| Acceso en línea: | https://doaj.org/article/c10338182b06464596106185eb9e2a79 |
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| Sumario: | Introduction: A reduced blood supply to lower limb, due to
arterial disease, is a common cause of foot ulceration in patients
with Diabetes Mellitus (DM). Impedance Plethysmography (IPG) is
based on the measurement of changes in the electrical resistance
(impedance) caused by blood volume changes.
Aim: To compare parameters of type-2 diabetic subjects with
those of healthy subjects along with different age group and
to associate with Blood Flow Index (BFI), Fasting Blood Sugar
(FBS), Post-Prandial Blood Sugar (PP2
BS) and Body Mass
Index (BMI).
Materials and Methods: This case-control study was conducted
at Government Medical College and in UHTC, Bhavnagar, Gujarat,
India, from May 2012 to August 2013 on 100 healthy subjects and
100 type-2 diabetic subjects. IPG arterial parameters like BFI,
Pulse Arrival Time (PAT), Pulse Termination Time (PTT), Differential
Pulse Arrival Time (DPAT), Z0 (Basal impedance) recorded. The
data were analysed by unpaired t-test and ANOVA test.
Results: This study had 200 subjects of age more than 30 years.
The diabetic subjects included 56 males and 44 females whereas
the healthy subjects included 67 males and 33 females. There
was bilateral significant reduction of BFI, PAT at knee, ankle and
calf segment among diabetics group in males and females; and
a bilateral significant reduction of PTT at ankle segment among
diabetic males and females. DPAT value increased at knee, calf
and ankle segment on both sides in male and female; except
right ankle segment in diabetic group in females as compared to
healthy subjects. Z0
increased at knee, ankle and calf segment in
diabetic group on both side in males and females. BFI decreased
with an increase in the duration of diabetes. The effect of FBS,
PP2
BS and BMI in diabetic subjects suggested a negative
association with BFI.
Conclusion: There was decrease in BFI, PAT, PTT and increase
in DPAT in the knee, calf and ankle region of diabetic subjects.
BFI negatively correlated with FBS, PP2
BS and BMI among
diabetics and decreased with increased duration of DM. |
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