Monoclonal Human Antibodies That Recognise the Exposed N and C Terminal Regions of the Often-Overlooked SARS-CoV-2 ORF3a Transmembrane Protein
ORF3a has been identified as a viroporin of SARS-CoV-2 and is known to be involved in various pathophysiological activities including disturbance of cellular calcium homeostasis, inflammasome activation, apoptosis induction and disruption of autophagy. ORF3a-targeting antibodies may specifically and...
Guardado en:
Autores principales: | Tyng Hwey Tan, Elizabeth Patton, Carol A. Munro, Dora E. Corzo-Leon, Andrew J. Porter, Soumya Palliyil |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/c10c6e519e564d23bd7c3db95d5ae027 |
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