Description of four cases of death by methanol: the experience of the toxicology and pharmacology laboratory of Moroccan Poison Control Centre

Introduction: Methanol intoxication is a public health problem that mainly affects poor populations in developed and developing countries. Despite all the advanced treatment methods, high mortality rates are still observed due to late admission to hospital and late diagnosis and treatment. Many mass...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Aït daoud Naima, Ghandi Mohamed, Chaoui Hanane, El Bouazzi Omaima, Zalagh Fatima, Abkari Asma, Soulaymani Abdelmajid, Soulaymani Bencheikh Rachida, Badrane Narjis, Benali Doha
Formato:	article
Lenguaje:	EN FR
Publicado:	EDP Sciences 2021
Materias:	mass poisoning death methanol dosage adulterated alcohol Environmental sciences GE1-350
Acceso en línea:	https://doaj.org/article/c10d1cafad204652a68d717b1fda9bc5
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:c10d1cafad204652a68d717b1fda9bc5
record_format	dspace
spelling	oai:doaj.org-article:c10d1cafad204652a68d717b1fda9bc52021-11-12T11:44:08ZDescription of four cases of death by methanol: the experience of the toxicology and pharmacology laboratory of Moroccan Poison Control Centre2267-124210.1051/e3sconf/202131901026https://doaj.org/article/c10d1cafad204652a68d717b1fda9bc52021-01-01T00:00:00Zhttps://www.e3s-conferences.org/articles/e3sconf/pdf/2021/95/e3sconf_vigisan_01026.pdfhttps://doaj.org/toc/2267-1242Introduction: Methanol intoxication is a public health problem that mainly affects poor populations in developed and developing countries. Despite all the advanced treatment methods, high mortality rates are still observed due to late admission to hospital and late diagnosis and treatment. Many mass poisoning have been described, following the misuse of methanol in the manufacture of adulterated alcohol in some Eastern European, Asian and African countries, resulting in several hundred each year. Objective: The objective of our study was to describe four cases of methanol intoxication that were received by the au toxicology and pharmacology laboratory of the Moroccan poison control centre CAPM-LAB. Materiel and methods: The epidemiological characteristics of patients intoxicated and dying by methanol in a collective setting were described as well as the results. Ethanol and methanol were determined in whole blood by gas chromatography with a flame ionisation detector coupled to the Head speace (CPG-FID-HS). Results: Following the consumption of adulterated alcohol (locally prepared alcohol); the CAPM-LAB received three samples from the city of El-Hajeb. The patients were aged of 46, 58 and 26 years and presented visual and consciousness disorders and vomiting, they presented average methanolemia of 1,34g/l. The CAPM-LAB also received samples from another patient from the city of Marrakech, aged 44 years, following a collective intoxication (three people) with adulterated alcohol, with methanol level of 2,52g/l. The patients died as a result of heart failure. Conclusion: Methanol can cause fatal intoxication, due to its easy availability in our country and the illegal production of alcoholic beverages.Aït daoud NaimaGhandi MohamedChaoui HananeEl Bouazzi OmaimaZalagh FatimaAbkari AsmaSoulaymani AbdelmajidSoulaymani Bencheikh RachidaBadrane NarjisBenali DohaEDP Sciencesarticlemass poisoningdeathmethanol dosageadulterated alcoholEnvironmental sciencesGE1-350ENFRE3S Web of Conferences, Vol 319, p 01026 (2021)
institution	DOAJ
collection	DOAJ
language	EN FR
topic	mass poisoning death methanol dosage adulterated alcohol Environmental sciences GE1-350
spellingShingle	mass poisoning death methanol dosage adulterated alcohol Environmental sciences GE1-350 Aït daoud Naima Ghandi Mohamed Chaoui Hanane El Bouazzi Omaima Zalagh Fatima Abkari Asma Soulaymani Abdelmajid Soulaymani Bencheikh Rachida Badrane Narjis Benali Doha Description of four cases of death by methanol: the experience of the toxicology and pharmacology laboratory of Moroccan Poison Control Centre
description	Introduction: Methanol intoxication is a public health problem that mainly affects poor populations in developed and developing countries. Despite all the advanced treatment methods, high mortality rates are still observed due to late admission to hospital and late diagnosis and treatment. Many mass poisoning have been described, following the misuse of methanol in the manufacture of adulterated alcohol in some Eastern European, Asian and African countries, resulting in several hundred each year. Objective: The objective of our study was to describe four cases of methanol intoxication that were received by the au toxicology and pharmacology laboratory of the Moroccan poison control centre CAPM-LAB. Materiel and methods: The epidemiological characteristics of patients intoxicated and dying by methanol in a collective setting were described as well as the results. Ethanol and methanol were determined in whole blood by gas chromatography with a flame ionisation detector coupled to the Head speace (CPG-FID-HS). Results: Following the consumption of adulterated alcohol (locally prepared alcohol); the CAPM-LAB received three samples from the city of El-Hajeb. The patients were aged of 46, 58 and 26 years and presented visual and consciousness disorders and vomiting, they presented average methanolemia of 1,34g/l. The CAPM-LAB also received samples from another patient from the city of Marrakech, aged 44 years, following a collective intoxication (three people) with adulterated alcohol, with methanol level of 2,52g/l. The patients died as a result of heart failure. Conclusion: Methanol can cause fatal intoxication, due to its easy availability in our country and the illegal production of alcoholic beverages.
format	article
author	Aït daoud Naima Ghandi Mohamed Chaoui Hanane El Bouazzi Omaima Zalagh Fatima Abkari Asma Soulaymani Abdelmajid Soulaymani Bencheikh Rachida Badrane Narjis Benali Doha
author_facet	Aït daoud Naima Ghandi Mohamed Chaoui Hanane El Bouazzi Omaima Zalagh Fatima Abkari Asma Soulaymani Abdelmajid Soulaymani Bencheikh Rachida Badrane Narjis Benali Doha
author_sort	Aït daoud Naima
title	Description of four cases of death by methanol: the experience of the toxicology and pharmacology laboratory of Moroccan Poison Control Centre
title_short	Description of four cases of death by methanol: the experience of the toxicology and pharmacology laboratory of Moroccan Poison Control Centre
title_full	Description of four cases of death by methanol: the experience of the toxicology and pharmacology laboratory of Moroccan Poison Control Centre
title_fullStr	Description of four cases of death by methanol: the experience of the toxicology and pharmacology laboratory of Moroccan Poison Control Centre
title_full_unstemmed	Description of four cases of death by methanol: the experience of the toxicology and pharmacology laboratory of Moroccan Poison Control Centre
title_sort	description of four cases of death by methanol: the experience of the toxicology and pharmacology laboratory of moroccan poison control centre
publisher	EDP Sciences
publishDate	2021
url	https://doaj.org/article/c10d1cafad204652a68d717b1fda9bc5
work_keys_str_mv	AT aitdaoudnaima descriptionoffourcasesofdeathbymethanoltheexperienceofthetoxicologyandpharmacologylaboratoryofmoroccanpoisoncontrolcentre AT ghandimohamed descriptionoffourcasesofdeathbymethanoltheexperienceofthetoxicologyandpharmacologylaboratoryofmoroccanpoisoncontrolcentre AT chaouihanane descriptionoffourcasesofdeathbymethanoltheexperienceofthetoxicologyandpharmacologylaboratoryofmoroccanpoisoncontrolcentre AT elbouazziomaima descriptionoffourcasesofdeathbymethanoltheexperienceofthetoxicologyandpharmacologylaboratoryofmoroccanpoisoncontrolcentre AT zalaghfatima descriptionoffourcasesofdeathbymethanoltheexperienceofthetoxicologyandpharmacologylaboratoryofmoroccanpoisoncontrolcentre AT abkariasma descriptionoffourcasesofdeathbymethanoltheexperienceofthetoxicologyandpharmacologylaboratoryofmoroccanpoisoncontrolcentre AT soulaymaniabdelmajid descriptionoffourcasesofdeathbymethanoltheexperienceofthetoxicologyandpharmacologylaboratoryofmoroccanpoisoncontrolcentre AT soulaymanibencheikhrachida descriptionoffourcasesofdeathbymethanoltheexperienceofthetoxicologyandpharmacologylaboratoryofmoroccanpoisoncontrolcentre AT badranenarjis descriptionoffourcasesofdeathbymethanoltheexperienceofthetoxicologyandpharmacologylaboratoryofmoroccanpoisoncontrolcentre AT benalidoha descriptionoffourcasesofdeathbymethanoltheexperienceofthetoxicologyandpharmacologylaboratoryofmoroccanpoisoncontrolcentre
_version_	1718430642462523392

Description of four cases of death by methanol: the experience of the toxicology and pharmacology laboratory of Moroccan Poison Control Centre

Ejemplares similares