Muscle progenitor specification and myogenic differentiation are associated with changes in chromatin topology

Chromatin structure and topology play important roles in the regulation of gene expression. Here the authors study the spatio-temporal re-organization of promoter-enhancer interactions in pluripotent ES and skeletal muscle stem cells and the corresponding impact on gene expression as a consequence o...

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Autores principales: Nan Zhang, Julen Mendieta-Esteban, Alessandro Magli, Karin C. Lilja, Rita C. R. Perlingeiro, Marc A. Marti-Renom, Aristotelis Tsirigos, Brian David Dynlacht
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/c1124748dba1487d92994b14a058a001
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spelling oai:doaj.org-article:c1124748dba1487d92994b14a058a0012021-12-02T14:40:40ZMuscle progenitor specification and myogenic differentiation are associated with changes in chromatin topology10.1038/s41467-020-19999-w2041-1723https://doaj.org/article/c1124748dba1487d92994b14a058a0012020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19999-whttps://doaj.org/toc/2041-1723Chromatin structure and topology play important roles in the regulation of gene expression. Here the authors study the spatio-temporal re-organization of promoter-enhancer interactions in pluripotent ES and skeletal muscle stem cells and the corresponding impact on gene expression as a consequence of myogenic commitment and differentiation.Nan ZhangJulen Mendieta-EstebanAlessandro MagliKarin C. LiljaRita C. R. PerlingeiroMarc A. Marti-RenomAristotelis TsirigosBrian David DynlachtNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Nan Zhang
Julen Mendieta-Esteban
Alessandro Magli
Karin C. Lilja
Rita C. R. Perlingeiro
Marc A. Marti-Renom
Aristotelis Tsirigos
Brian David Dynlacht
Muscle progenitor specification and myogenic differentiation are associated with changes in chromatin topology
description Chromatin structure and topology play important roles in the regulation of gene expression. Here the authors study the spatio-temporal re-organization of promoter-enhancer interactions in pluripotent ES and skeletal muscle stem cells and the corresponding impact on gene expression as a consequence of myogenic commitment and differentiation.
format article
author Nan Zhang
Julen Mendieta-Esteban
Alessandro Magli
Karin C. Lilja
Rita C. R. Perlingeiro
Marc A. Marti-Renom
Aristotelis Tsirigos
Brian David Dynlacht
author_facet Nan Zhang
Julen Mendieta-Esteban
Alessandro Magli
Karin C. Lilja
Rita C. R. Perlingeiro
Marc A. Marti-Renom
Aristotelis Tsirigos
Brian David Dynlacht
author_sort Nan Zhang
title Muscle progenitor specification and myogenic differentiation are associated with changes in chromatin topology
title_short Muscle progenitor specification and myogenic differentiation are associated with changes in chromatin topology
title_full Muscle progenitor specification and myogenic differentiation are associated with changes in chromatin topology
title_fullStr Muscle progenitor specification and myogenic differentiation are associated with changes in chromatin topology
title_full_unstemmed Muscle progenitor specification and myogenic differentiation are associated with changes in chromatin topology
title_sort muscle progenitor specification and myogenic differentiation are associated with changes in chromatin topology
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/c1124748dba1487d92994b14a058a001
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