Muscle progenitor specification and myogenic differentiation are associated with changes in chromatin topology
Chromatin structure and topology play important roles in the regulation of gene expression. Here the authors study the spatio-temporal re-organization of promoter-enhancer interactions in pluripotent ES and skeletal muscle stem cells and the corresponding impact on gene expression as a consequence o...
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Nature Portfolio
2020
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oai:doaj.org-article:c1124748dba1487d92994b14a058a0012021-12-02T14:40:40ZMuscle progenitor specification and myogenic differentiation are associated with changes in chromatin topology10.1038/s41467-020-19999-w2041-1723https://doaj.org/article/c1124748dba1487d92994b14a058a0012020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19999-whttps://doaj.org/toc/2041-1723Chromatin structure and topology play important roles in the regulation of gene expression. Here the authors study the spatio-temporal re-organization of promoter-enhancer interactions in pluripotent ES and skeletal muscle stem cells and the corresponding impact on gene expression as a consequence of myogenic commitment and differentiation.Nan ZhangJulen Mendieta-EstebanAlessandro MagliKarin C. LiljaRita C. R. PerlingeiroMarc A. Marti-RenomAristotelis TsirigosBrian David DynlachtNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-18 (2020) |
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Science Q Nan Zhang Julen Mendieta-Esteban Alessandro Magli Karin C. Lilja Rita C. R. Perlingeiro Marc A. Marti-Renom Aristotelis Tsirigos Brian David Dynlacht Muscle progenitor specification and myogenic differentiation are associated with changes in chromatin topology |
description |
Chromatin structure and topology play important roles in the regulation of gene expression. Here the authors study the spatio-temporal re-organization of promoter-enhancer interactions in pluripotent ES and skeletal muscle stem cells and the corresponding impact on gene expression as a consequence of myogenic commitment and differentiation. |
format |
article |
author |
Nan Zhang Julen Mendieta-Esteban Alessandro Magli Karin C. Lilja Rita C. R. Perlingeiro Marc A. Marti-Renom Aristotelis Tsirigos Brian David Dynlacht |
author_facet |
Nan Zhang Julen Mendieta-Esteban Alessandro Magli Karin C. Lilja Rita C. R. Perlingeiro Marc A. Marti-Renom Aristotelis Tsirigos Brian David Dynlacht |
author_sort |
Nan Zhang |
title |
Muscle progenitor specification and myogenic differentiation are associated with changes in chromatin topology |
title_short |
Muscle progenitor specification and myogenic differentiation are associated with changes in chromatin topology |
title_full |
Muscle progenitor specification and myogenic differentiation are associated with changes in chromatin topology |
title_fullStr |
Muscle progenitor specification and myogenic differentiation are associated with changes in chromatin topology |
title_full_unstemmed |
Muscle progenitor specification and myogenic differentiation are associated with changes in chromatin topology |
title_sort |
muscle progenitor specification and myogenic differentiation are associated with changes in chromatin topology |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/c1124748dba1487d92994b14a058a001 |
work_keys_str_mv |
AT nanzhang muscleprogenitorspecificationandmyogenicdifferentiationareassociatedwithchangesinchromatintopology AT julenmendietaesteban muscleprogenitorspecificationandmyogenicdifferentiationareassociatedwithchangesinchromatintopology AT alessandromagli muscleprogenitorspecificationandmyogenicdifferentiationareassociatedwithchangesinchromatintopology AT karinclilja muscleprogenitorspecificationandmyogenicdifferentiationareassociatedwithchangesinchromatintopology AT ritacrperlingeiro muscleprogenitorspecificationandmyogenicdifferentiationareassociatedwithchangesinchromatintopology AT marcamartirenom muscleprogenitorspecificationandmyogenicdifferentiationareassociatedwithchangesinchromatintopology AT aristotelistsirigos muscleprogenitorspecificationandmyogenicdifferentiationareassociatedwithchangesinchromatintopology AT briandaviddynlacht muscleprogenitorspecificationandmyogenicdifferentiationareassociatedwithchangesinchromatintopology |
_version_ |
1718390196139982848 |