Comparative Study between Microscopic and Endoscopic Endonasal Trans-Sphenoidal Surgeries for Nonfunctioning Pituitary Macro-Adenomas

Background: The transsphenoidal surgery has emerged as the standard treatment of pituitary adenomas. The endonasal transsphenoidal approach either microscopic or endoscopic affords a rhinological recovery with fewer sinonasal complaints.Aim of the work: Comparison between microscopic and endoscopic...

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Autores principales: Mohammed Abdel Fattah, Mohammed Abu Shahba, Mohammed Hassan, Hatem Elsamouly
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Publicado: Al-Azhar University, Faculty of Medicine (Damietta) 2021
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spelling oai:doaj.org-article:c113a087546a4204882d9aa25f321b462021-12-02T19:36:37ZComparative Study between Microscopic and Endoscopic Endonasal Trans-Sphenoidal Surgeries for Nonfunctioning Pituitary Macro-Adenomas2636-41742682-378010.21608/ijma.2021.83666.1335https://doaj.org/article/c113a087546a4204882d9aa25f321b462021-10-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_203495_7bbcb5dfe41086c864ee2591a24e7505.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: The transsphenoidal surgery has emerged as the standard treatment of pituitary adenomas. The endonasal transsphenoidal approach either microscopic or endoscopic affords a rhinological recovery with fewer sinonasal complaints.Aim of the work: Comparison between microscopic and endoscopic endonasal trans-sphenoidal approaches in nonfunctioning pituitary adenomas.Patients and Methods: Thirty patients with nonfunctioning pituitary adenomas were included from March 2015 to October 2020. The patients were subdivided into two groups, Group [A]: 15 patients for an endoscopic endonasal transsphenoidal approach, and Group [B]: 15 patients for microscopic endonasal transsphenoidal approach. All patients were subjected to history taking, general and neurological examination, visual, rhinological, endocrine and radiological assessment. All patients were followed up and examined by an attending neurosurgeon, otolaryngologist and endocrinologist one and three months and then yearly thereafter. The data were obtained and recorded. Complete tumor resection was the primary outcome. Other secondary outcomes included operative data and postoperative complications.Results: Operative time ranged from 60.0 - 150.0 minutes [mean 108.0 and 88.0 minutes in groups A and B respectively]. Complete tumor resection achieved in 13 patients [86.7%] of group A compared to 10 patients [66.7%] in group B. Subtotal tumor resection achieved for 2 patients [13.3%] and 3 patients [20%] of groups A and B, respectively.  Partial resection and insufficient removal was reported in one patient [6.7%] for each in group B.Conclusion: The endoscopic endonasal approach provides more favorable tumor removal, and hence was associated improved visual field and acuity, less postoperative pain and shorter hospitalization.Mohammed Abdel FattahMohammed Abu ShahbaMohammed HassanHatem ElsamoulyAl-Azhar University, Faculty of Medicine (Damietta)articlenon-functioning pituitary tumorsmicroscopicendoscopicendonasaltranssphenoidalMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 3, Iss 4, Pp 1941-1946 (2021)
institution DOAJ
collection DOAJ
language EN
topic non-functioning pituitary tumors
microscopic
endoscopic
endonasal
transsphenoidal
Medicine (General)
R5-920
spellingShingle non-functioning pituitary tumors
microscopic
endoscopic
endonasal
transsphenoidal
Medicine (General)
R5-920
Mohammed Abdel Fattah
Mohammed Abu Shahba
Mohammed Hassan
Hatem Elsamouly
Comparative Study between Microscopic and Endoscopic Endonasal Trans-Sphenoidal Surgeries for Nonfunctioning Pituitary Macro-Adenomas
description Background: The transsphenoidal surgery has emerged as the standard treatment of pituitary adenomas. The endonasal transsphenoidal approach either microscopic or endoscopic affords a rhinological recovery with fewer sinonasal complaints.Aim of the work: Comparison between microscopic and endoscopic endonasal trans-sphenoidal approaches in nonfunctioning pituitary adenomas.Patients and Methods: Thirty patients with nonfunctioning pituitary adenomas were included from March 2015 to October 2020. The patients were subdivided into two groups, Group [A]: 15 patients for an endoscopic endonasal transsphenoidal approach, and Group [B]: 15 patients for microscopic endonasal transsphenoidal approach. All patients were subjected to history taking, general and neurological examination, visual, rhinological, endocrine and radiological assessment. All patients were followed up and examined by an attending neurosurgeon, otolaryngologist and endocrinologist one and three months and then yearly thereafter. The data were obtained and recorded. Complete tumor resection was the primary outcome. Other secondary outcomes included operative data and postoperative complications.Results: Operative time ranged from 60.0 - 150.0 minutes [mean 108.0 and 88.0 minutes in groups A and B respectively]. Complete tumor resection achieved in 13 patients [86.7%] of group A compared to 10 patients [66.7%] in group B. Subtotal tumor resection achieved for 2 patients [13.3%] and 3 patients [20%] of groups A and B, respectively.  Partial resection and insufficient removal was reported in one patient [6.7%] for each in group B.Conclusion: The endoscopic endonasal approach provides more favorable tumor removal, and hence was associated improved visual field and acuity, less postoperative pain and shorter hospitalization.
format article
author Mohammed Abdel Fattah
Mohammed Abu Shahba
Mohammed Hassan
Hatem Elsamouly
author_facet Mohammed Abdel Fattah
Mohammed Abu Shahba
Mohammed Hassan
Hatem Elsamouly
author_sort Mohammed Abdel Fattah
title Comparative Study between Microscopic and Endoscopic Endonasal Trans-Sphenoidal Surgeries for Nonfunctioning Pituitary Macro-Adenomas
title_short Comparative Study between Microscopic and Endoscopic Endonasal Trans-Sphenoidal Surgeries for Nonfunctioning Pituitary Macro-Adenomas
title_full Comparative Study between Microscopic and Endoscopic Endonasal Trans-Sphenoidal Surgeries for Nonfunctioning Pituitary Macro-Adenomas
title_fullStr Comparative Study between Microscopic and Endoscopic Endonasal Trans-Sphenoidal Surgeries for Nonfunctioning Pituitary Macro-Adenomas
title_full_unstemmed Comparative Study between Microscopic and Endoscopic Endonasal Trans-Sphenoidal Surgeries for Nonfunctioning Pituitary Macro-Adenomas
title_sort comparative study between microscopic and endoscopic endonasal trans-sphenoidal surgeries for nonfunctioning pituitary macro-adenomas
publisher Al-Azhar University, Faculty of Medicine (Damietta)
publishDate 2021
url https://doaj.org/article/c113a087546a4204882d9aa25f321b46
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AT mohammedabushahba comparativestudybetweenmicroscopicandendoscopicendonasaltranssphenoidalsurgeriesfornonfunctioningpituitarymacroadenomas
AT mohammedhassan comparativestudybetweenmicroscopicandendoscopicendonasaltranssphenoidalsurgeriesfornonfunctioningpituitarymacroadenomas
AT hatemelsamouly comparativestudybetweenmicroscopicandendoscopicendonasaltranssphenoidalsurgeriesfornonfunctioningpituitarymacroadenomas
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