Marital status, depressive episodes, and short-term prognosis of patients with acute coronary syndrome: Greek study of acute coronary syndrome (GREECS)

Demosthenes B Panagiotakos1,3, Christos Pitsavos2,3, Yannis Kogias3, Yannis Mantas3, Spyros Zombolos3, Antonis Antonoulas3, George Giannopoulos2, Christina Chrysohoou2, Christodoulos Stefanadis11Office of Biostatistics – Epidemiology, Department of Nutrition – Dietetics,...

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Autores principales: Demosthenes B Panagiotakos, Christos Pitsavos, Yannis Kogias, Yannis Mantas, Spyros Zombolos, et al
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Publicado: Dove Medical Press 2008
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spelling oai:doaj.org-article:c117c2a5cb90447ba4d5f45fa8eab62a2021-12-02T08:37:28ZMarital status, depressive episodes, and short-term prognosis of patients with acute coronary syndrome: Greek study of acute coronary syndrome (GREECS)1176-63281178-2021https://doaj.org/article/c117c2a5cb90447ba4d5f45fa8eab62a2008-04-01T00:00:00Zhttp://www.dovepress.com/marital-status-depressive-episodes-and-short-term-prognosis-of-patient-a1031https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Demosthenes B Panagiotakos1,3, Christos Pitsavos2,3, Yannis Kogias3, Yannis Mantas3, Spyros Zombolos3, Antonis Antonoulas3, George Giannopoulos2, Christina Chrysohoou2, Christodoulos Stefanadis11Office of Biostatistics – Epidemiology, Department of Nutrition – Dietetics, Harokopio University, Athens, Greece; 2First Cardiology Clinic, School of Medicine, University of Athens, Greece; 3The GREECS Study Investigators, GreeceAbstract: The association between marital status and short-term prognosis of patients hospitalized for acute coronary syndrome (ACS) was evaluated. From October 2003 to September 2004, a sample of 6 hospitals located in Greek regions was selected, and almost all survivors after an ACS were enrolled into the study (2172 patients were included in the study; 76% were men). The in-hospital mortality rate was 3.2% in male patients and 5.7% in female patients (p = 0.009). Never-married patients had 2.8-times higher risk of dying during hospitalization compared with married, after adjusting for various confounders (p < 0.01, attributable risk = 64%). Furthermore, never-married had 2.7-times higher risk of dying during the first 30-days following hospitalization compared with married (p < 0.01, attributable risk = 62%). Moderate depressive symptoms 3.26-fold (95% CI 1.40–7.11) the risk of recurrent events, while severe depressive symptoms were associated with 8.2-fold (95% CI 3.98–17.1) higher risk of events. No interaction was observed between marital status and depression on 30-day prognosis of ACS patients (p > 0.5). People who were not-married and depressed at the time of an acute cardiac episode were at higher risk of fatal events than people who were married, irrespective of depression status and other characteristics.Keywords: marital status, acute coronary syndromes, risk Demosthenes B PanagiotakosChristos PitsavosYannis KogiasYannis MantasSpyros Zomboloset alDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2008, Iss Issue 2, Pp 425-432 (2008)
institution DOAJ
collection DOAJ
language EN
topic Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
spellingShingle Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
Demosthenes B Panagiotakos
Christos Pitsavos
Yannis Kogias
Yannis Mantas
Spyros Zombolos
et al
Marital status, depressive episodes, and short-term prognosis of patients with acute coronary syndrome: Greek study of acute coronary syndrome (GREECS)
description Demosthenes B Panagiotakos1,3, Christos Pitsavos2,3, Yannis Kogias3, Yannis Mantas3, Spyros Zombolos3, Antonis Antonoulas3, George Giannopoulos2, Christina Chrysohoou2, Christodoulos Stefanadis11Office of Biostatistics – Epidemiology, Department of Nutrition – Dietetics, Harokopio University, Athens, Greece; 2First Cardiology Clinic, School of Medicine, University of Athens, Greece; 3The GREECS Study Investigators, GreeceAbstract: The association between marital status and short-term prognosis of patients hospitalized for acute coronary syndrome (ACS) was evaluated. From October 2003 to September 2004, a sample of 6 hospitals located in Greek regions was selected, and almost all survivors after an ACS were enrolled into the study (2172 patients were included in the study; 76% were men). The in-hospital mortality rate was 3.2% in male patients and 5.7% in female patients (p = 0.009). Never-married patients had 2.8-times higher risk of dying during hospitalization compared with married, after adjusting for various confounders (p < 0.01, attributable risk = 64%). Furthermore, never-married had 2.7-times higher risk of dying during the first 30-days following hospitalization compared with married (p < 0.01, attributable risk = 62%). Moderate depressive symptoms 3.26-fold (95% CI 1.40–7.11) the risk of recurrent events, while severe depressive symptoms were associated with 8.2-fold (95% CI 3.98–17.1) higher risk of events. No interaction was observed between marital status and depression on 30-day prognosis of ACS patients (p > 0.5). People who were not-married and depressed at the time of an acute cardiac episode were at higher risk of fatal events than people who were married, irrespective of depression status and other characteristics.Keywords: marital status, acute coronary syndromes, risk
format article
author Demosthenes B Panagiotakos
Christos Pitsavos
Yannis Kogias
Yannis Mantas
Spyros Zombolos
et al
author_facet Demosthenes B Panagiotakos
Christos Pitsavos
Yannis Kogias
Yannis Mantas
Spyros Zombolos
et al
author_sort Demosthenes B Panagiotakos
title Marital status, depressive episodes, and short-term prognosis of patients with acute coronary syndrome: Greek study of acute coronary syndrome (GREECS)
title_short Marital status, depressive episodes, and short-term prognosis of patients with acute coronary syndrome: Greek study of acute coronary syndrome (GREECS)
title_full Marital status, depressive episodes, and short-term prognosis of patients with acute coronary syndrome: Greek study of acute coronary syndrome (GREECS)
title_fullStr Marital status, depressive episodes, and short-term prognosis of patients with acute coronary syndrome: Greek study of acute coronary syndrome (GREECS)
title_full_unstemmed Marital status, depressive episodes, and short-term prognosis of patients with acute coronary syndrome: Greek study of acute coronary syndrome (GREECS)
title_sort marital status, depressive episodes, and short-term prognosis of patients with acute coronary syndrome: greek study of acute coronary syndrome (greecs)
publisher Dove Medical Press
publishDate 2008
url https://doaj.org/article/c117c2a5cb90447ba4d5f45fa8eab62a
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