SOX17 regulates uterine epithelial–stromal cross-talk acting via a distal enhancer upstream of Ihh

The transcription factor SOX17 is important for uterine gland formation, fertility, and embryo implantation in mouse. Here the authors show that SOX17 is upstream of Indian hedgehog to regulate mouse uterine receptivity, and their analysis of uterine tissue from endometriosis patients suggests the s...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Xiaoqiu Wang, Xilong Li, Tianyuan Wang, San-Pin Wu, Jae-Wook Jeong, Tae Hoon Kim, Steven L. Young, Bruce A. Lessey, Rainer B. Lanz, John P. Lydon, Francesco J. DeMayo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c127c07db61c403ebeb300e9a82a357d
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:c127c07db61c403ebeb300e9a82a357d
record_format	dspace
spelling	oai:doaj.org-article:c127c07db61c403ebeb300e9a82a357d2021-12-02T17:32:00ZSOX17 regulates uterine epithelial–stromal cross-talk acting via a distal enhancer upstream of Ihh10.1038/s41467-018-06652-w2041-1723https://doaj.org/article/c127c07db61c403ebeb300e9a82a357d2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06652-whttps://doaj.org/toc/2041-1723The transcription factor SOX17 is important for uterine gland formation, fertility, and embryo implantation in mouse. Here the authors show that SOX17 is upstream of Indian hedgehog to regulate mouse uterine receptivity, and their analysis of uterine tissue from endometriosis patients suggests the same function in humans.Xiaoqiu WangXilong LiTianyuan WangSan-Pin WuJae-Wook JeongTae Hoon KimSteven L. YoungBruce A. LesseyRainer B. LanzJohn P. LydonFrancesco J. DeMayoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xiaoqiu Wang Xilong Li Tianyuan Wang San-Pin Wu Jae-Wook Jeong Tae Hoon Kim Steven L. Young Bruce A. Lessey Rainer B. Lanz John P. Lydon Francesco J. DeMayo SOX17 regulates uterine epithelial–stromal cross-talk acting via a distal enhancer upstream of Ihh
description	The transcription factor SOX17 is important for uterine gland formation, fertility, and embryo implantation in mouse. Here the authors show that SOX17 is upstream of Indian hedgehog to regulate mouse uterine receptivity, and their analysis of uterine tissue from endometriosis patients suggests the same function in humans.
format	article
author	Xiaoqiu Wang Xilong Li Tianyuan Wang San-Pin Wu Jae-Wook Jeong Tae Hoon Kim Steven L. Young Bruce A. Lessey Rainer B. Lanz John P. Lydon Francesco J. DeMayo
author_facet	Xiaoqiu Wang Xilong Li Tianyuan Wang San-Pin Wu Jae-Wook Jeong Tae Hoon Kim Steven L. Young Bruce A. Lessey Rainer B. Lanz John P. Lydon Francesco J. DeMayo
author_sort	Xiaoqiu Wang
title	SOX17 regulates uterine epithelial–stromal cross-talk acting via a distal enhancer upstream of Ihh
title_short	SOX17 regulates uterine epithelial–stromal cross-talk acting via a distal enhancer upstream of Ihh
title_full	SOX17 regulates uterine epithelial–stromal cross-talk acting via a distal enhancer upstream of Ihh
title_fullStr	SOX17 regulates uterine epithelial–stromal cross-talk acting via a distal enhancer upstream of Ihh
title_full_unstemmed	SOX17 regulates uterine epithelial–stromal cross-talk acting via a distal enhancer upstream of Ihh
title_sort	sox17 regulates uterine epithelial–stromal cross-talk acting via a distal enhancer upstream of ihh
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/c127c07db61c403ebeb300e9a82a357d
work_keys_str_mv	AT xiaoqiuwang sox17regulatesuterineepithelialstromalcrosstalkactingviaadistalenhancerupstreamofihh AT xilongli sox17regulatesuterineepithelialstromalcrosstalkactingviaadistalenhancerupstreamofihh AT tianyuanwang sox17regulatesuterineepithelialstromalcrosstalkactingviaadistalenhancerupstreamofihh AT sanpinwu sox17regulatesuterineepithelialstromalcrosstalkactingviaadistalenhancerupstreamofihh AT jaewookjeong sox17regulatesuterineepithelialstromalcrosstalkactingviaadistalenhancerupstreamofihh AT taehoonkim sox17regulatesuterineepithelialstromalcrosstalkactingviaadistalenhancerupstreamofihh AT stevenlyoung sox17regulatesuterineepithelialstromalcrosstalkactingviaadistalenhancerupstreamofihh AT brucealessey sox17regulatesuterineepithelialstromalcrosstalkactingviaadistalenhancerupstreamofihh AT rainerblanz sox17regulatesuterineepithelialstromalcrosstalkactingviaadistalenhancerupstreamofihh AT johnplydon sox17regulatesuterineepithelialstromalcrosstalkactingviaadistalenhancerupstreamofihh AT francescojdemayo sox17regulatesuterineepithelialstromalcrosstalkactingviaadistalenhancerupstreamofihh
_version_	1718380453785763840

SOX17 regulates uterine epithelial–stromal cross-talk acting via a distal enhancer upstream of Ihh

Ejemplares similares