A human ESC line for efficient CRISPR editing of pluripotent stem cells
Human pluripotent stem cells (hPSC) can be directed to differentiate in vitro into insulin-prorducing beta cells (SC-β). Although these cells accurately respond to glucose and can reverse diabetes in preclinical models improvments in the final cell products are desirable. For example, safety, contro...
Guardado en:
Autores principales: | Elad Sintov, Dario Gerace, Douglas A. Melton |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/c13124af03dd436c9fac4750b2a61845 |
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